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Cytochrome C Oxidase Subunit II (COX2)

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MTCO2; MT-CO2; COII; COXII; Mitochondrially Encoded Cytochrome C Oxidase II; Cytochrome c oxidase polypeptide II

Cytochrome C Oxidase Subunit II (COX2)
CCC D284
HGNC 7421
MGI 102503
PubMed 12612644
RGD 621872
UniProt P00403
Wiki COX2
Cytochrome c oxidase subunit II is a human protein belongs to cytochrome c oxidase subunit II protein family. It is sometimes confused with the cyclooxygenase enzyme COX-2.Cytochrome c oxidase subunit II, abbreviated CoxII, is the second subunit of cytochrome c oxidase. Cytochrome c oxidase (EC 1.9.3.1) is an oligomeric enzymatic complex which is a component of the respiratory chain and is involved in the transfer of electrons from cytochrome c to oxygen. In eukaryotes this enzyme complex is located in the mitochondrial inner membrane; in aerobic prokaryotes it is found in the plasma membrane. The enzyme complex consists of 3-4 subunits (prokaryotes) to up to 13 polypeptides (mammals). In Leigh's disease, there may be an abnormality or deficiency of cytochrome oxidase.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD284Hu01 Recombinant Cytochrome C Oxidase Subunit II (COX2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Cytochrome C Oxidase Subunit II (COX2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome C Oxidase Subunit II (COX2) Polyclonal Antibody Customized Service Offer
Assay Kits SED284Hu ELISA Kit for Cytochrome C Oxidase Subunit II (COX2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome C Oxidase Subunit II (COX2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome C Oxidase Subunit II (COX2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome C Oxidase Subunit II (COX2) Polyclonal Antibody Customized Service Offer
Assay Kits SED284Mu ELISA Kit for Cytochrome C Oxidase Subunit II (COX2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD284Ra01 Recombinant Cytochrome C Oxidase Subunit II (COX2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD284Ra01 Polyclonal Antibody to Cytochrome C Oxidase Subunit II (COX2) WB; IHC
Assay Kits SED284Ra ELISA Kit for Cytochrome C Oxidase Subunit II (COX2) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Sequence and organization of the human mitochondrial genome."Nature 290:457-465(1981) [PubMed] [Europe PMC] [Abstract]
  2. "Nucleotide sequence of human mitochondrial cytochrome c oxidase II cDNA."Nucleic Acids Res. 17:6734-6734(1989) [PubMed] [Europe PMC] [Abstract]
  3. "A different genetic code in human mitochondria."Nature 282:189-194(1979) [PubMed] [Europe PMC] [Abstract]
  4. "Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs."Proc. Natl. Acad. Sci. U.S.A. 92:532-536(1995) [PubMed] [Europe PMC] [Abstract]
  5. "Mitochondrial COII sequences and modern human origins."Mol. Biol. Evol. 10:1115-1135(1993) [PubMed] [Europe PMC] [Abstract]
  6. "Lineage-specific selection in human mtDNA: lack of polymorphisms in a segment of MTND5 gene in haplogroup J."Mol. Biol. Evol. 20:2132-2142(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Mitochondrial genome variation and the origin of modern humans."Nature 408:708-713(2000) [PubMed] [Europe PMC] [Abstract]
  8. "Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines."Genome Res. 13:1600-1606(2003) [PubMed] [Europe PMC] [Abstract]
  9. "Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians."Int. J. Legal Med. 118:137-146(2004) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  12. "Normal variants of human mitochondrial DNA and translation products: the building of a reference data base."Hum. Genet. 88:139-145(1991) [PubMed] [Europe PMC] [Abstract]
  13. "Somatic mutations of the mitochondrial genome in human colorectal tumours."Nat. Genet. 20:291-293(1998) [PubMed] [Europe PMC] [Abstract]
  14. "A missense mutation of cytochrome oxidase subunit II causes defective assembly and myopathy."Am. J. Hum. Genet. 65:1030-1039(1999) [PubMed] [Europe PMC] [Abstract]