Interleukin 8 Receptor Beta (IL8Rb)

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CD182; CDw128b; IL8R-B; IL8-RB; CMKAR2; CXCR2; IL8R2; C-X-C chemokine receptor type 2; GRO/MGSA receptor; High affinity interleukin-8 receptor B

Interleukin 8 Receptor Beta (IL8Rb)

Interleukin 8 receptor, beta is a chemokine receptor. IL8RB is also known as CXCR2, and CXCR2 is now the IUPHAR Committee on Receptor Nomenclature and Drug classification-recommended name.The protein encoded by this gene is a member of the G-protein coupled receptor family.

This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. In addition, it binds ligands CXCL2, CXCL3, and CXCL5.
 

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC006Hu01 Recombinant Interleukin 8 Receptor Beta (IL8Rb) Positive Control; Immunogen; SDS-PAGE; WB.
CPC006Hu21 OVA Conjugated Interleukin 8 Receptor Beta (IL8Rb) Immunogen; SDS-PAGE; WB.
Antibodies PAC006Hu01 Polyclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
MAC006Hu21 Monoclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB
PAC006Hu09 Polyclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
MAC006Hu24 Monoclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
MAC006Hu25 Monoclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
MAC006Hu22 Monoclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
MAC006Hu23 Monoclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
Assay Kits SEC006Hu ELISA Kit for Interleukin 8 Receptor Beta (IL8Rb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC006Mu01 Recombinant Interleukin 8 Receptor Beta (IL8Rb) Positive Control; Immunogen; SDS-PAGE; WB.
RPC006Mu02 Recombinant Interleukin 8 Receptor Beta (IL8Rb) Positive Control; Immunogen; SDS-PAGE; WB.
CPC006Mu21 OVA Conjugated Interleukin 8 Receptor Beta (IL8Rb) Immunogen; SDS-PAGE; WB.
SPC006Mu01 Synthetic Interleukin 8 Receptor Beta (IL8Rb) Immunogen; Blocking Peptide.
Antibodies PAC006Mu01 Polyclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
PAC006Mu02 Polyclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
PAC006Mu08 Polyclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
Assay Kits SEC006Mu ELISA Kit for Interleukin 8 Receptor Beta (IL8Rb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC006Ra01 Recombinant Interleukin 8 Receptor Beta (IL8Rb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC006Ra01 Polyclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
MAC006Ra21 Monoclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) WB; IHC; ICC; IP.
Assay Kits SEC006Ra ELISA Kit for Interleukin 8 Receptor Beta (IL8Rb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interleukin 8 Receptor Beta (IL8Rb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interleukin 8 Receptor Beta (IL8Rb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 8 Receptor Beta (IL8Rb) ELISA Kit Customized Service Offer
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  8. "Ligand-induced desensitization of the human CXC chemokine receptor-2 is modulated by multiple serine residues in the carboxyl-terminal domain of the receptor."J. Biol. Chem. 272:8207-8214(1997) [PubMed] [Europe PMC] [Abstract]