Ficolin 3 (FCN3)
[Edit]FCNH; HAKA1; Collagen/Fibrinogen Domain Containing; Hakata Antigen; Collagen/fibrinogen domain-containing lectin 3 p35
Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. Ficolin-3 can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB903Hu01 | Recombinant Ficolin 3 (FCN3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB903Hu01 | Polyclonal Antibody to Ficolin 3 (FCN3) | WB |
MAB903Hu22 | Monoclonal Antibody to Ficolin 3 (FCN3) | WB; IHC; ICC; IP. | |
Assay Kits | SEB903Hu | ELISA Kit for Ficolin 3 (FCN3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ficolin 3 (FCN3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ficolin 3 (FCN3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ficolin 3 (FCN3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEB903Mu | ELISA Kit for Ficolin 3 (FCN3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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- "In silico designed structure of ficolin precursor."Submitted (NOV-2002) to the PDB data bank