Fatty Acid Binding Protein 2, Intestinal (FABP2)
[Edit]FABPI; IFABP; I-FABP; Intestinal-type fatty acid-binding protein
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The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation.
Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA559Hu01 | Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA559Hu61 | Eukaryotic Fatty Acid Binding Protein 2, Intestinal (FABP2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA559Hu01 | Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) | WB; IHC; ICC; IP. |
| MAA559Hu22 | Monoclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) | WB; IHC; ICC; IP. | |
| PAA559Hu06 | Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA559Hu | ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| HEA559Hu | High Sensitive ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA559Po01 | Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA559Po01 | Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) | WB; IHC; ICC; IP. |
| Assay Kits | SEA559Po | ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA559Bo01 | Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA559Bo01 | Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) | ELISA Kit Customized Service Offer |
Organism species: Chicken (Gallus)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA559Ga01 | Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | SEA559Ga | ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Intestinal-type and liver-type fatty acid-binding protein in the intestine. Tissue distribution and clinical utility."Clin. Biochem. 36:529-535(2003) [PubMed] [Europe PMC] [Abstract]
- "Epidermal growth factor regulates fatty acid uptake and metabolism in Caco-2 cells."Am. J. Physiol. 276:G606-G612(1999) [PubMed] [Europe PMC] [Abstract]
- "Consequences of single-site mutations in the intestinal fatty acid binding protein."Biochemistry 42:12192-12199(2003) [PubMed] [Europe PMC] [Abstract]
- "Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit."J. Biomol. NMR 9:213-228(1997) [PubMed] [Europe PMC] [Abstract]
- "Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism."Biochemistry 42:7339-7347(2003) [PubMed] [Europe PMC] [Abstract]
- "An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance."J. Clin. Invest. 95:1281-1287(1995) [PubMed] [Europe PMC] [Abstract]
- "The association of Ala54Thr variant of intestinal fatty acid binding protein gene with general and regional adipose tissue depots."Chin. Med. Sci. J. 14:46-51(1999) [PubMed] [Europe PMC] [Abstract]