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Recombinant Complement Component 3a (C3a)

  • Product No.RPA387Po01
  • Organism SpeciesSus scrofa; Porcine (Pig) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass38.7kDa
  • Accurate Molecular Mass42kDa(Analysis of differences refer to the manual)
  • Residues & TagsSer670~Leu742 with N-terminal His and GST Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point8.2
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 188  US$ 470  US$ 940  US$ 2820  US$ 7050 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in PBS or others.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
22 Immobilization of soluble complement receptor 1 on islets. ScienceDirect: S0142961211002596
Journal of Reproductive Immunology Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia PubMed: 23415845
Journal of Antimicrobial Chemotherapy Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model Pubmed: 23645587
SpringerPlus Therapeutic effects of sesame oil on monosodium urate crystal-induced acute inflammatory response in rats Pubmed: 24353977
Gynecol Obstet Invest Complement Split Products C3a/C5a and Receptors: Are They Regulated by Circulating Angiotensin II Type 1 Receptor Autoantibody in Severe Preeclampsia? PubMed: 26485247
Am J Reprod Immunol Human IgG Antinuclear Antibodies Induce Pregnancy Loss in Mice by Increasing Immune Complex Deposition in Placental Tissue: In Vivo Study PubMed: 26388133
Journal of Neuroimmunology Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis Pubmed:27235358
Plos One Alternative Pathway Inhibition by Exogenous Factor H Fails to Attenuate Inflammation and Vascular Leakage in Experimental Pneumococcal Sepsis in Mice Pubmed:26872035
Digital Repository Dosagem de frações ativadas do sistema complemento em empiema induzido em ratos 10183
Colloids Surf B Biointerfaces. Interaction of gold and silver nanoparticles with human plasma: Analysis of protein corona reveals specific binding patterns. pubmed:28131092
Pediatric Pulmonology Accuracy of complement activation product levels to detect infected pleural effusion in rats pubmed:28474458
Journal of Immunology The Complement C3a–C3aR Axis Promotes Development of Thoracic Aortic Dissection via Regulation of MMP2 Expression Pubmed:29367209
Artificial Cells Nanomedicine and Biotechnology Journal Long term safety and immunological effects of a nanobiotherapeutic, bovine poly-[hemoglobin-catalase-superoxide dismutase-carbonic anhydrase], after four weekly … Pubmed:29873524
Cytotherapy Mesenchymal stromal cell secretory factors induce sustained improvements in islet function pre-and post-transplantation Doi: 10.1016/j.jcyt.2018.07.007
Journal of NeuroVirology Intrathecal complement activation by the classical pathway in tick-borne encephalitis Pubmed: 30850976
Clinical Immunology Pathogenic roles of anti-C1q antibodies in recurrent pregnancy loss
Materials Science and Engineering: C Hemocompatibility of biodegradable Zn-0.8 wt%(Cu, Mn, Li) alloys
Nanomedicine Complement-mediated hypersensitivity reactions to an amphotericin B-containing lipid complex (Abelcet) in pediatric patients and anesthetized rats: Benefits of slow infusion 33549818
EXPERIMENTAL EYE RESEARCH Increased ratios of complement factors C3a to C3 in aqueous humor and serum mark glaucoma progression 33493474
FASEB J C‐reactive protein inhibits C3a/C3aR‐dependent podocyte autophagy in favor of diabetic kidney disease Pubmed:35503088
Catalog No. Related products for research use of Sus scrofa; Porcine (Pig) Organism species Applications (RESEARCH USE ONLY!)
RPA387Po01 Recombinant Complement Component 3a (C3a) Positive Control; Immunogen; SDS-PAGE; WB.
PAA387Po01 Polyclonal Antibody to Complement Component 3a (C3a) WB; IHC; ICC; IP.
MAA387Po23 Monoclonal Antibody to Complement Component 3a (C3a) WB; IHC; ICC; IP.
MAA387Po24 Monoclonal Antibody to Complement Component 3a (C3a) WB; IHC; ICC; IP.
MAA387Po21 Monoclonal Antibody to Complement Component 3a (C3a) WB; IHC; ICC; IP.
MAA387Po22 Monoclonal Antibody to Complement Component 3a (C3a) WB; IHC; ICC; IP.
SEA387Po ELISA Kit for Complement Component 3a (C3a) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA387Po CLIA Kit for Complement Component 3a (C3a) Chemiluminescent immunoassay for Antigen Detection.
LMA387Po Multiplex Assay Kit for Complement Component 3a (C3a) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.