Polyclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)

FH3; HCHOLA3; NARC1; Hypercholesterolemia,Autosomal Dominant 3; Neural apoptosis-regulated convertase 1; Proprotein convertase 9; Subtilisin/kexin-like protease PC9

Product No.PAE189Mu01
Organism SpeciesMus musculus (Mouse) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
SourcePolyclonal antibody preparation
HostRabbit
Potencyn/a
Ig Type IgG
PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
LabelNone
Immunogen RPE189Mu01-Recombinant Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)
Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
TraitsLiquid
Concentration0.5mg/mL
Organism Species MoreRattus norvegicus (Rat)
ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
DownloadInstruction Manual
UOM 20µl100µl 200µl 1ml 10ml
FOB US$ 108 252 US$ 252 US$ 360 US$ 900 US$ 3600
For more details, please contact local distributors!

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against PCSK9. It has been selected for its ability to recognize PCSK9 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine	Citations
Biological Trace Element Research	Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers pubmed:28409410
BASIC RESEARCH IN CARDIOLOGY	Autocrine effects of PCSK9 on cardiomyocytes Pubmed: 33169229
J Transl Med	Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans 33407555
Metabolism	MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice 33775647
Eur Rev Med Pharmacol Sci	Association of serum proprotein convertase Subtilisin/Kexin Type 9 (PCSK9) level with thyroid function disorders 34533801
Clin Exp Hypertens	Proprotein convertase subtilisin/kexin type 9 is associated with atherosclerosis in patients with Behcet's disease Pubmed:35502687

Catalog No.	Related products for research use of Mus musculus (Mouse) Organism species	Applications (RESEARCH USE ONLY!)
APE189Mu01	Active Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)	Cell culture; Activity Assays.
RPE189Mu02	Recombinant Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)	Positive Control; Immunogen; SDS-PAGE; WB.
RPE189Mu01	Recombinant Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)	Positive Control; Immunogen; SDS-PAGE; WB.
PAE189Mu01	Polyclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)	WB; IHC; ICC; IP.
PAE189Mu02	Polyclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)	WB; IHC; ICC; IP.
SEE189Mu	ELISA Kit for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)	Enzyme-linked immunosorbent assay for Antigen Detection.
AEE189Mu	ELISA Kit for Anti-Proprotein Convertase Subtilisin/Kexin Type 9 Antibody (Anti-PCSK9)	Enzyme-linked immunosorbent assay for Antibody Detection.
LME189Mu	Multiplex Assay Kit for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) ,etc. by FLIA (Flow Luminescence Immunoassay)	FLIA Kit for Antigen Detection.