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Polyclonal Antibody to Serglycin (SRGN)

PRG; PPG; PRG1; proteoglycan 1, secretory granule

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against SRGN. It has been selected for its ability to recognize SRGN in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Irish Journal of Medical Science The role of increased synovial fluid A disintegrin and metalloproteinase with thrombospondin motifs4 and serglycin levels in osteoarthritis Pubmed: 30536194
MOLECULAR AND CELLULAR BIOCHEMISTRY SRGN, a new identified shear-stress-responsive gene in endothelial cells Pubmed: 32712749
Theranostics Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer 33456569
CELLULAR ONCOLOGY Cancer©\associated fibroblasts secrete hypoxia©\induced serglycin to promote head and neck squamous cell carcinoma tumor cell growth in vitro and in vivo by ¡­ 33651283
Cell Death Dis Serglycin induces osteoclastogenesis and promotes tumor growth in giant cell tumor of bone 34556636
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPC869Ra02 Recombinant Serglycin (SRGN) Positive Control; Immunogen; SDS-PAGE; WB.
RPC869Ra01 Recombinant Serglycin (SRGN) Positive Control; Immunogen; SDS-PAGE; WB.
PAC869Ra02 Polyclonal Antibody to Serglycin (SRGN) WB; IHC; ICC; IP.