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Polyclonal Antibody to Complement Component 5 (C5)

CPAMD4; C5a anaphylatoxin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against C5. It has been selected for its ability to recognize C5 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Journal of Clinical Immunology Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease. PubMed: 22941511
Journal of Neuroimmunology Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis Pubmed:27235358
Cancer Letters Complement C5a/C5aR pathway potentiates the pathogenesis Q5 of gastric cancer by down-regulating p21 expression pubmed:29031586
Proteomics Clinical Applications iTRAQ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism Pubmed:29274201
American journal of physiology. Endocrinology and metabolism Impaired insulin signaling in the B10.D2-Hc H2 H2-T18/oSnJ mouse model of complement factor 5 (C5) deficiency Pubmed: 31084499
Proteomics Clinical Applications Comparative proteomics analysis of serum proteins in gestational diabetes during early and middle stages of pregnancy Pubmed: 31162828
Aging C5aR deficiency attenuates the breast cancer development via the p38/p21 axis Pubmed: 32669478
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPB969Mu02 Recombinant Complement Component 5 (C5) Positive Control; Immunogen; SDS-PAGE; WB.
RPB969Mu01 Recombinant Complement Component 5 (C5) Positive Control; Immunogen; SDS-PAGE; WB.
PAB969Mu01 Polyclonal Antibody to Complement Component 5 (C5) WB; IHC; ICC; IP.
PAB969Mu02 Polyclonal Antibody to Complement Component 5 (C5) WB; IHC; ICC; IP.
WEB969Mu Wide-range ELISA Kit for Complement Component 5 (C5) Enzyme-linked immunosorbent assay for Antigen Detection.
SEB969Mu ELISA Kit for Complement Component 5 (C5) Enzyme-linked immunosorbent assay for Antigen Detection.
MEB969Mu Mini Samples ELISA Kit for Complement Component 5 (C5) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB969Mu Multiplex Assay Kit for Complement Component 5 (C5) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.