Polyclonal Antibody to C Reactive Protein (CRP)
C-RP; PTX1; Pentraxin-Related; Pentraxin 1
- Product No.PAA821Hu02
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourcePolyclonal antibody preparation
- HostRabbit
- Potencyn/a
- Ig Type IgG
- PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
- LabelNone
- Immunogen NPA821Hu01-Native C Reactive Protein (CRP)
- Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
- TraitsLiquid
- Concentration0.5mg/mL
- Organism Species MoreMus musculus (Mouse), Rattus norvegicus (Rat), Sus scrofa; Porcine (Pig)
- ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies. - DownloadInstruction Manual
- UOM 20µl100µl 200µl 1ml 10ml
- FOB
US$ 68
For more details, please contact local distributors! US$ 160 US$ 228 US$ 570 US$ 2280
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against CRP. It has been selected for its ability to recognize CRP in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
GIVEAWAYS
INCREMENT SERVICES
- Antibody Labeling Customized Service
- Protein A/G Purification Column
- Staining Solution for Cells and Tissue
- Positive Control for Antibody
- Tissue/Sections Customized Service
- Phosphorylated Antibody Customized Service
- Western Blot (WB) Experiment Service
- Immunohistochemistry (IHC) Experiment Service
- Immunocytochemistry (ICC) Experiment Service
- Flow Cytometry (FCM) Experiment Service
- Immunoprecipitation (IP) Experiment Service
- Immunofluorescence (IF) Experiment Service
- Buffer
- DAB Chromogen Kit
- SABC Kit
- Long-arm Biotin Labeling Kit
- Real Time PCR Experimental Service
Magazine | Citations |
Journalof Vascular Research | Effect of Hirulog-Like Peptide on Balloon Catheter Injury-Induced Neointimal Formation in Femoral Arteries of Minipigs and Relationship with Inflammatory Mediators Karger: 000257340 |
Journal of Pharmacology and Experimental Therapeutics | Successful Treatment of Acute Lung Injury with Pitavastatin in Septic Mice: Potential Role of Glucocorticoid Receptor Expression in Alveolar Macrophages Aspet: 171462 |
Experimental Animals | Anti-Inflammatory Effect of Guan-Xin-Er-Hao via the Nuclear Factor-Kappa B Signaling Pathway in Rats with Acute Myocardial Infarction Jstage: source |
Neuroscience | In vivo protective effect of ferulic acid against noise-induced hearing loss in the guinea-pig PubMed: 20600667 |
Heart and Vessels | Metformin inhibits nuclear factor κB activation and decreases serum high-sensitivity C-reactive protein level in experimental atherogenesis of rabbits SpringerLink: pt732478620w1528 |
Plos one | Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial PubMed: 23516412 |
Psychosomatic Medicine | Unpredictable chronic mild stress promotes atherosclerosis in high cholesterol-fed rabbits PubMed: 22753638 |
PLOS ONE | Protective Effect of Curcumin on Pulmonary and Cardiovascular Effects Induced by Repeated Exposure to Diesel Exhaust Particles in Mice PlosOne: Source |
BMC Neurology | Relationships among serum C-reactive protein, receptor for advanced glycation products, metabolic dysfunction, and cognitive impairments PubMed: PMC3765839 |
Particle and fibre toxicology, | Impact of experimental type 1 diabetes mellitus on systemic and coagulation vulnerability in mice acutely exposed to diesel exhaust particles PubMed: PMC3641025 |
Clinics | Changes in body weight, C-reactive protein, and total adiponectin in non-obese women after 12 months of a small-volume, home-based exercise program PubMed: PMC3752622 |
PLoS One | Pre-Pubertal Children Born Post-Term Have Reduced Insulin Sensitivity and Other Markers of the Metabolic Syndrome PubMed: PMC3698136 |
Scientific Report | Among overweight middle-aged men, first-borns have lower insulin sensitivity than second-borns Pubmed: 24503677 |
International Urology Nephrology | Perirenal fat associated with microalbuminuria in obese rats Pubmed: 24526332 |
AJBM | Effect of caffeic acid on doxorubicin induced cardiotoxicity in rats Ajbm: Source |
Journal of Molecular and Cellular Cardiology | Effect of high free fatty acids on the anti-contractile response of perivascular adipose tissue in rat aorta Pubmed: 23939490 |
PLoS One. | Flos Lonicera Ameliorates Obesity and Associated Endotoxemia in Rats through Modulation of Gut Permeability and Intestinal Microbiota Plos: Source |
Fundamental & Clinical Pharmacology | The determination of histopathological and biochemical effects of the rabbit knee joint injected dexketoprofen trometamol Onlinelibrary: fcp.12074 |
Mainz | Identifizierung neuer potentieller Biomarker für das Kolonkarzinom sowie dessen Vorstufen Info:Source |
Int J Clin Exp Med. | Celastrol may have an anti-atherosclerosis effect in a rabbit experimental carotid atherosclerosis model Pubmed:Pmc4132129 |
International Urology and Nephrology | As If Biomarker Discovery Isn't Hard Enough: The Consequences of Poorly Characterized Reagents Pubmed:24305687 |
Nutr Res. | Curcumin attenuates adhesion molecules and matrix metalloproteinase expression in hypercholesterolemic rabbits Pubmed:25282128 |
Journal of Obstetrics and Gynaecology Research | Regression of experimental endometriotic implants in a rat model with the angiotensin II receptor blocker losartan Pubmed:25302540 |
Chemical Research in Toxicology | Sub-chronic Toxicity and Cardiovascular Responses in Spontaneously Hypertensive Rats after Exposure to Multiwall Carbon Nanotubes by Intratracheal Instillation Pubmed:25580880 |
Journal of Applied Toxicology | Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits Pubmed:25619500 |
Cellular Physiology and Biochemistry | Short-Term Nose-Only Water-Pipe (Shisha) Smoking Exposure Accelerates Coagulation and Causes Cardiac Inflammation and Oxidative Stress in Mice Pubmed:25634761 |
Food and Chemical Toxicology | Consumption of orange fermented beverage reduces cardiovascular risk factors in healthy mice Pubmed:25666657 |
Cellular Physiology and Biochemistry | Induction of Haemeoxygenase-1 Improves FFA-Induced Endothelial Dysfunction in Rat Aorta Pubmed:25766533 |
天津中医药大学学报 | 巨噬细胞及其相关因子在家兔不稳定斑块中的作用及其机制 Paper:Source |
Mediators of Inflammation | Effects of Intravenous Injection of PubMed: 26063970 |
Am J Physiol Heart Circ Physiol | Irisin improves endothelial function in obese mice through the AMPK-eNOS pathway PubMed: 26371167 |
Cell Physiol Biochem | Induction of Haemeoxygenase-1 Directly Improves Endothelial Function in Isolated Aortas from Obese Rats through the Ampk-Pi3k/Akt-Enos Pathway PubMed: 26160485 |
Exp Physiol | Renal protective effects of induction of haem oxygenase-1 combined with increased adiponectin on the glomerular vascular endothelial growth factor–nitric oxide axis in obese rats PubMed: 25959017 |
Clin Oral Investig | Can apical periodontitis affect serum levels of CRP, IL-2, and IL-6 as well as induce pathological changes in remote organs? PubMed: 26556576 |
Chemical Research in Toxicology | Subchronic Toxicity and Cardiovascular Responses in Spontaneously Hypertensive Rats after Exposure to Multiwalled Carbon Nanotubes by Intratracheal Instillation PubMed: 25580880 |
Acta Biomater | Resveratrol Inhibited Inflammation andAlveolar Bone Loss in Periodontitis PubMed: 26497626 |
Archives of Physiology and Biochemistry | Activation of cardiac renin–angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder Pubmed:26934364 |
Journal of Functional Foods | Orange beverage ameliorates high-fat-diet-induced metabolic disorder in mice article:S1756464616300688 |
Medical Science Monitor | Variation of Circulating Inflammatory Mediators in Staphylococcus aureus and Escherichia coli BloodstreamInfection. Pubmed:26772168 |
J Diabetes Res. | Central Administration of Galanin Receptor 1 Agonist Boosted Insulin Sensitivity in Adipose Cells of Diabetic Rats pmc:PMC4835658 |
Asian J Pharm Clin Res | THE ANTI-HYPERCHOLESTEROLEMIC EFFECT OF ULVAN POLYSACCHARIDE EXTRACTED FROM THE GREEN ALGA ULVAFASCIATA ON AGED HYPERCHOLESTEROLEMIC RATS journals:10835 |
J Bone Miner Res | Fat and Sucrose Intake Induces Obesity‐Related Bone Metabolism Disturbances: Kinetic and Reversibility Studies in Growing and Adult Rats Pubmed:26175082 |
Naunyn-Schmiedeberg's Archives of Pharmacology | Combined oral contraceptive-induced hypertension is accompanied by endothelial dysfunction and upregulated intrarenal angiotensin II type 1 receptor gene expression pubmed:27447455 |
Journal of Coastal Life Medicine | Cardioprotective and renoprotective effects of Cocos nucifera water in offspring of high fat diet fed Wistar rat dams qk:20168 |
Journal of Functional Foods | Eicosapentaenoic acid-enriched phospholipids improve atherosclerosis by mediating cholesterol metabolism S1756464617300890 |
Environmental toxicology and pharmacology | Combined oral contraceptive and nitric oxide synthesis inhibition synergistically causes cardiac hypertrophy and exacerbates insulin resistance in female rats. pubmed:28376377 |
Andrology | Chronic prostatitis/chronic pelvic pain syndrome impairs erectile function through increased endothelial dysfunction, oxidative stress, apoptosis, and corporal fibrosis … doi:10.1111 |
Journal of Diabetes Research | Central administration of galanin receptor 1 agonist boosted insulin sensitivity in adipose pubmed:27127795 |
Therapeutics and Clinical Risk Management | Elevated blood plasma levels of epinephrine, norepinephrine, tyrosine hydroxylase, TGFβ1, and TNFα associated with high-altitude pulmonary edema in an Indian population. pubmed:27540296 |
Veterinary World | Acute phase response in lame crossbred dairy cattle pubmed:27956769 |
J Ethnopharmacol | Anti-atherosclerosis and cardio-protective effects of the Angong Niuhuang Pill on a high fat and vitamin D3 induced rodent model of atherosclerosis. pubmed:27880884 |
SHOCK | INTERLEUKIN-1 RECEPTOR 2: A NEW BIOMARKER FOR SEPSIS DIAGNOSIS AND GRAM-NEGATIVE/GRAM-POSITIVE BACTERIAL DIFFERENTIATION pubmed:27984536 |
International Surgery | PROCALCITONIN, C-REACTIVE PROTEIN AND FIBRINOGEN LEVELS IN CASES WITH MECHANIC BOWEL OBSTRUCTION AND THEIR CHANGE IN RELATION TO THE DURATION OF OBSTRUCTION: AN EXPERIMENTAL STUDY 10.3892/ol.2017.7301 |
CORONARY ARTERY DISEASE | Relationship of mean platelet volume to lymphocyte ratio and coronary collateral circulation in patients with stable angina pectoris pubmed:28678144 |
Biomedicine & Pharmacotherapy | Protective effect of α–lipoic acid against spleen toxicity of dimethylnitrosamine in male mice: Antioxidant and ultrastructure approaches pubmed:29031205 |
PLoS One | The effects of non-surgical periodontal treatment on glycemic control, oxidative stress balance and quality of life in patients with type 2 diabetes: A randomized clinical trial pubmed:29145468 |
Poultry Science | The effect of DL-, L-isomers and DL-hydroxy analog administered at 2 levels as dietary sources of methionine on the metabolic and antioxidant parameters and growth performance of turkeys 10.3382/ps/pex099 |
Oncotarget | The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis. pubmed:29029533 |
International Journal of Cuban Health & Medicine | Anemia and Iron Deficiency Related to Inflammation, Helicobacter pylori Infection and Adiposity in Reproductive-age Cuban Women 10.1590/MEDICC.2017.1902030004 |
Korean Journal of Internal Medicine | The relationship between anti-C-reactive protein and disease activity in patients with systemic lupus erythematosus. pubmed:28352058 |
Biomedical and Environmental Sciences | Grape Seed Procyanidin Extract Reduces Arsenic-Induced Renal Inflammatory Injury in Male Mice. pubmed:28756814 |
Pharmacological reports | Anti-inflammatory and antithrombotic effects of nicotine exposure in oral contraceptive-induced insulin resistance are glucocorticoid-independent pubmed:28349880 |
Nature Communications | A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense Pubmed:29410422 |
International Journal of Obesity | Leptin alleviates intestinal mucosal barrier injury and inflammation in obese mice with acute pancreatitis Pubmed:29934609 |
Molecular Nutrition & Food Research | The Protective Activities of Dietary Sea Cucumber Cerebrosides Against Atherosclerosis Through Regulating Inflammation and Cholesterol Metabolism in Male Mice Pubmed:29883529 |
Oxidative Medicine and Cellular Longevity | Changes of Plasma FABP4, CRP, Leptin, and Chemerin Levels in relation to Different Dietary Patterns and Duodenal-Jejunal Omega Switch Surgery in Sprague … Pubmed:29849871 |
Nutrients | L-Carnitine Supplementation in Older Women. A Pilot Study on Aging Skeletal Muscle Mass and Function Pubmed:29473908 |
Journal of Functional Foods | Saponins of sea cucumber attenuate atherosclerosis in ApoE−/− mice via lipid-lowering and anti-inflammatory properties 10.1016:j.jff.2018.07.046 |
Veterinary immunology and immunopathology | Generation and validation of novel anti-bovine CD163 monoclonal antibodies ABM-1A9 and ABM-2D6 Pubmed:29571519 |
Journal of Experimental Animal Science | Oxymatrine attenuates lipopolysaccharide-induced acute lung injury by activating the epithelial sodium channel and suppressing the JNK signaling pathway Pubmed:29526865 |
Journal of Young Pharmacists | Anti-Inflammatory Activity of Combined Aerodisperse System in the Conditions of Experimental Cervical Lymphadenite : |
Journal of Pharmacological Sciences | Improved endogenous epoxyeicosatrienoic acid production mends heart function via increased PGC 1α-mitochondrial functions in metabolic syndrome Pubmed: 30342783 |
The Egyptian Rheumatologist | Sonographic synovitis in primary knee osteoarthritis patients and its relation to biomarkers of inflammation and oxidative stress Doi: 10.1016/j.ejr.2018.12.004 |
West Indian Medical Journal | Plasma Cellular Hypoxia, Mitochondrial Dysfunction, Disease Risk and Prognostic Factors in Type 2 Diabetic Patients in Saudi Arabia. |
Nutrition & Metabolism | L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women Pubmed: 30485835 |
The Egyptian Rheumatologist | The Egyptian Rheumatologist |
Experimental Biology and Medicine | Grape seed proanthocyanidin extract alleviates arsenic-induced lung damage through NF-κB signaling Pubmed: 30869553 |
International Journal of Inflammation | Morphological Characteristics of the Thymus and Spleen and the Subpopulation Composition of Lymphocytes in Peripheral Blood during Systemic Inflammatory … |
Journal of Central European Agriculture | Novel assay for the detection of CRP protein in rabbit leukocytes using flow cytometry |
Journal of Clinical Medicine | Periodontal Health and Oral Microbiota in Patients with Rheumatoid Arthritis Pubmed: 31072030 |
Journal of Applied Pharmaceutical Science | Effects of Eurycoma longifolia Jack on chronic cerebral hypoperfusion-induced oxidative damage and memory deficit in rats |
Food & Function | Eicosapentaenoic acid in the form of phospholipid exerts superior anti-atherosclerosis effects than its triglyceride form in ApoE-/-mice |
Journal of Central European Agriculture | Novel assay for the detection of CRP protein in rabbit leukocytes using flow cytometry/Nova metoda detekcie CRP proteinu na kralicich leukocytoch pomocou … |
Food and Chemical Toxicology | The potential efficacy of dietary fatty acids and fructose induced inflammation and oxidative stress on the insulin signaling and fat accumulation in mice Pubmed: 31672515 |
Journal of Controlled Release | Ginsenoside Rg3-loaded, reactive oxygen species-responsive polymeric nanoparticles for alleviating myocardial ischemia-reperfusion injury Pubmed: 31783047 |
Nutrients | Rotundic Acid Protects against Metabolic Disturbance and Improves Gut Microbiota in Type 2 Diabetes Rats Pubmed: 31887996 |
Food & Function | Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial Pubmed: 32044905 |
JOURNAL OF HAZARDOUS MATERIALS | Silica nanoparticles induce JNK-mediated inflammation and myocardial contractile dysfunction Pubmed: 32036317 |
Cell Transplant | The Efficacy of Autologous Myoblast Sheet Transplantation to Prevent Perforation After Duodenal Endoscopic Submucosal Dissection in Porcine Model Pubmed: 33121270 |
Nanotoxicology | miR-205/IRAK2 signaling pathway is associated with urban airborne PM2.5-induced myocardial toxicity Pubmed: 32880512 |
Journal of the American Society of Echocardiography | Protective Effects of Statin and Angiotensin Receptor Blocker in a Rat Model of Doxorubicin-and Trastuzumab-Induced Cardiomyopathy Pubmed: 32778498 |
disease markers | Association between Plasma Sestrin2 Levels and the Presence and Severity of Coronary Artery Disease Pubmed: 32670435 |
Scientific Reports | Integrated metabolomics and gut microbiome to the effects and mechanisms of naoxintong capsule on type 2 diabetes in rats Pubmed: 32616735 |
animal reproduction science | Quantifying the C-reactive protein concentrations of uterine lavage samples in postpartum dairy cows Pubmed: 32408965 |
ANNALS OF TRANSLATIONAL MEDICINE | Serum levels of olfactomedin 4: a biomarker for asthma control state in asthmatics Pubmed: 32395538 |
nutrition | Validation and adaptation of the Empirical Dietary Inflammatory Pattern (EDIP) across nations: a test case. Pubmed: 32563770 |
European Journal of Biology | Effects of Tempol in Lipopolysaccharide-Induced Liver Injury |
Possible Role of Statins on the Inflammatory Biomarkers in Patients With Periodontal Disease: A Cross-Sectional Study | |
International Journal of Oral Science | Endothelin-1 is a surrogate biomarker link severe periodontitis and endothelial dysfunction in hypertensive patients: The potential nexus |
Indian Journal of Animal Research | Effect of claw disorders on haemato-biochemical parameters and acute phase protein levels in crossbred cattle |
Lateral Flow Immunosensor for Ferritin Based on Dual Signal-Amplified Strategy by Rhodium Nanoparticles | |
Early label-free analysis of mitochondrial redox states by Raman spectroscopy predicts septic outcomes | |
МАРКЕРЫ КОСТНОГО РЕМОДЕЛИРОВАНИЯ ПРИ ЗАМЕЩЕНИИ ДЕФЕКТАТРАБЕКУЛЯРНОЙ КОСТНОЙ ТКАНИ РЕЗОРБИРУЕМЫМИ И … | |
J Transl Med | Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans 33407555 |
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | Use of Fourier-Transform Infrared Spectroscopy (FT-IR) for Monitoring Experimental Helicobacter pylori Infection and Related Inflammatory Response in Guinea Pig?¡ 33396581 |
Sci Rep | Ileal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl: ZUC (ORL)-Lepr fa) rats 33833309 |
Mol Med Rep | Baicalin relieves Mycoplasma pneumoniae infection?induced lung injury through regulating microRNA?221 to inhibit the TLR4/NF?¦ÊB signaling pathway 34109422 |
Nutrients | Prevalence and Factors Associated with Iron Deficiency and Anemia among Residents of Urban Areas of S?o Paulo, Brazil 34072813 |
peerj | Perfluorooctane sulfonate exerts inflammatory bowel disease-like intestinal injury in rats 33510972 |
Biomed Pharmacother | Intravenous ferric carboxymaltose does not provide benefits in reperfused acute myocardial infarction in the rat with normal iron status 34243097 |
Aging | Pim-2 kinase inhibits inflammation by suppressing the mTORC1 pathway in atherosclerosis 34547720 |
Analytical and Bioanalytical Chemistry | Nets of biotin-derived gold nanoparticles as a label for the C-reactive protein immunoassay 34559243 |
J Oleo Sci | Cardio-protective and Anti-atherosclerosis Effect of Crocetin on Vitamin D3 and HFD-induced Atherosclerosis in Rats 34615830 |
Medicine | Early-stage serum Stanniocalcin 1 as a predictor of outcome in patients with aneurysmal subarachnoid hemorrhage Pubmed:34941085 |
Talanta | A rapid fluorescent aptasensor for point-of-care detection of C-reactive protein Pubmed:35714415 |
Experimental and Therapeutic Medicine | Construction of a rabbit model with vinorelbine administration via peripherally inserted central catheter and dynamic monitoring of changes in phlebitis and thrombosis Pubmed:35126715 |
Sensors and Actuators B: Chemical | A Two-step Competition Assay for Visual, Sensitive and Quantitative C-reactive Protein Detection in Low-cost Microfluidic Particle Accumulators |