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Polyclonal Antibody to Endothelin 1 (EDN1)

ET1; PPET1; Preproendothelin-1; Big endothelin-1

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against EDN1. It has been selected for its ability to recognize EDN1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;1:220-900
Immunohistochemistry: 5-20µg/mL;1:22-90
Immunocytochemistry: 5-20µg/mL;1:22-90
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Heart and Circulatory Physiology B-type natriuretic peptide, vascular endothelial growth factor, endothelin-1, and nitric oxide synthase in chronic mountain sickness APS: source
PLOS ONE CD98 Positive Eosinophils Contribute to T Helper 1 Pattern Inflammation PlosOne: Source
36 Megakaryocytic leukemia 1 (MKL1) ties the epigenetic machinery to hypoxia-induced transactivation of endothelin-1 PubMed: PMC3695508
Clinics (Sao Paulo). Antifibrotic effects of crocetin in scleroderma fibroblasts and in bleomycin-induced sclerotic mice Pubmed: 24212843
Life Sci. Attenuation of renal ischemia/reperfusion injury by a?aí extract preconditioning in a rat model Pubmed:25476829
Transpl Int. One or 4 h of “in‐house” reconditioning by machine perfusion after cold storage improve reperfusion parameters in porcine kidneys Pubmed:24977654
J Endocrinol Invest.? The interplay among iron metabolism, endothelium and inflammatory cascade in dysmetabolic disorders Pubmed:25245337
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Journal of Surgical Research Pivotal role of mast cell carboxypeptidase A in mediating protection against small intestinal ischemia–reperfusion injury in rats after ischemic preconditioning Sciencedirect:S0022480414004909
Pharmaceutical Biology The promising effect of barberry (Zereshk) extract against experimental pulmonary microvascular remodeling and hypertension: A comparison with sildenafil PubMed: 26023989
A Periodical of the Hungarian Academy of Sciences The effect of high altitude on endothelial and vascular dysfunction markers in preeclamptic patients PubMed: 26690031
Chemical Research in Toxicology Subchronic Toxicity and Cardiovascular Responses in Spontaneously Hypertensive Rats after Exposure to Multiwalled Carbon Nanotubes by Intratracheal Instillation PubMed: 25580880
Human & Experimental Toxicology An in vivo and in vitro study High-dosage Danshen injection induces peripheral vascular endothelial cells injury PubMed: 26078283
Artery Research Endothelin 1 and endothelial dysfunction in children with idiopathic nephrotic syndrome science:article
Transplant  proc Cardiovascular Risk Factors and Markers of Atherosclerosis in Stable Kidney TransplantRecipients. pubmed:27496444
Biomed Journal Association of endothelial dysfunction and cytotoxin-associated gene A-positive Helicobacter pylori in patients with cardiac syndrome X. pubmed:27884380
International Journal of Advanced Research in Biological Sciences Comparative studies on lens structure and function of newborn rats maternally treated with aspartame, monosodium glutamate and galactose pdfcopy:42552
Journal of Drug Metabolisn& Toxicology Abnormal Retinal Structure and Function of Mother Wistar Rats Supplemented Aspartame, Glutamate and Galactose 587e5b6508aed3826af45e2d.pdf
Polish Journal of Veterinary Sciences Antioxidant and anti-inflammatory activities of a commercial noni juice revealed by carrageenan-induced paw edema pubmed:27760029
Artery Research Endothelin 1 and endothelial dysfunction in children with idiopathic nephrotic syndrome article:S1872-9312(16)30085-0
Journal of Molecular Biomarkers J & Diagnosis Biochemical and Molecular Markers of Congenital and Senile Cataractous Lenses DOI: 10.4172/2155-9929.1000318
A Study of Effect of Experimental Pre-Eclampsia on Plasma Lipocalin-2 Level in Rats. AN=123819331
Journal of Functional Foods Antihypertensive effects of Ocimum gratissimumextract: Angiotensin-converting enzyme inhibitor in vitro and in vivo investigation 10.1016/j.jff.2017.05.033
Radiation Research Selective Insulin-like Growth Factor Resistance Associated with Heart Hemorrhages and Poor Prognosis in a Novel Preclinical Model of the Hematopoietic Acute … Pubmed:29809108
Scandinavian Journal of Clinical and Laboratory Investigation Isolated kidney perfusion: the influence of pulsatile flow Pubmed:29301417
Endokrynologia Polska Endothelin-1 (ET-1), N-terminal fragment of proatrial natriuretic peptide (NTpro-ANP) and tumor necrosis factor alpha (TNF-α) in children with primary hypertension … Pubmed: 30359461
Journal of Pharmacological Sciences Improved endogenous epoxyeicosatrienoic acid production mends heart function via increased PGC 1α-mitochondrial functions in metabolic syndrome Pubmed: 30342783
Molecular Nutrition & Food Research Short‐Term Isocaloric Intake of a Fructose‐but not Glucose‐Rich Diet Affects Bacterial Endotoxin Concentrations and Markers of Metabolic Health in Normal Weight … Pubmed: 30570214
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Eurasian Journal of Clinical Sciences APASL Single Topic Conference DELTA HEPATITIS, 27-28 June 2019, Baku, Azerbaijan
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Scientific Reports Integrated metabolomics and gut microbiome to the effects and mechanisms of naoxintong capsule on type 2 diabetes in rats Pubmed: 32616735
Evidence-Based Complementary and Alternative Medicine Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats Pubmed: 33133215
Microvasc Res Effect of liraglutide on microcirculation in rat model with absolute insulin deficiency 34119534
Biomed Pharmacother Tianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti … 34736077
J Ethnopharmacol Bai-Hu-Tang regulates endothelin-1 and its signalling pathway in vascular endothelial cells 34752899
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Optical Technologies for Biology and Medicine Laser Doppler flowmetry in assessing the effect of liraglutide on microcirculation in rats with absolute insulin deficiency
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