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Monoclonal Antibody to Telomerase Reverse Transcriptase (TERT)

EST2; TCS1; TP2; TRT; hEST2; Telomerase catalytic subunit; Telomerase-associated protein 2

SPECIFITY

The antibody is a mouse monoclonal antibody raised against TERT. It has been selected for its ability to recognize TERT in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Journal of Physiological Anthropology Telomeres are elongated in rats exposed to moderate altitude Pubmed:Pmc4088304
Exp Ther Med Thymocytes maintain immune activity through telomere elongation in rats under hypoxic conditions PubMed: 26640565
Journal of Physiological Anthropology Telomere elongation protects heart and lung tissue cells from fatal damage in rats exposed to severe hypoxia Pubmed:29454386
Respiratory Medicine Coexistence of obstructive sleep apnea and telomerase activity, concentration of selected adipose tissue hormones and vascular endothelial function in patients with …
Stress Maternal neglect results in reduced telomerase activity and increased oxidative load in rats Pubmed: 32588701
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Reversal of brain aging by targeting telomerase: A nutraceutical approach 34515324
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