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Monoclonal Antibody to Lymphocyte Activation Gene 3 (LAG3)

CD223; Protein FDC

SPECIFITY

The antibody is a mouse monoclonal antibody raised against LAG3. It has been selected for its ability to recognize LAG3 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-4µg/mL;
Immunofluorescence: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Biosensors and Bioelectronics A signal-decreased electrochemical immunosensor for the sensitive detection of LAG-3 protein based on a hollow nanobox-MOFs/AuPt alloy Pubmed:29772383
Cancer Biomarkers Soluble LAG3 acts as a potential prognostic marker of gastric cancer and its positive correlation with CD8+ T cell frequency and secretion of IL-12 and INF-γ in … Pubmed: 30223387
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