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Monoclonal Antibody to Glutathione Reductase (GR)

GSR; GLUR; GRD1; Glutathione reductase, mitochondrial

  • Product No.MAB314Ra21
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 115  US$ 267  US$ 382  US$ 955  US$ 3820 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against GR. It has been selected for its ability to recognize GR in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Oxidative Medicine and Cellular Longevity Doxorubicin Toxicity can be Ameliorated during Antioxidant L-Carnitine Supplementation PubMed: PMC3154045
PLoS One. P2×7?Receptor in the Kidneys of Diabetic Rats Submitted to Aerobic Training or to N-Acetylcysteine Supplementation Plos:Source
Diabetes/Metabolism Research and Reviews Reduced peripheral blood mtDNA content is associated with impaired glucose‐stimulated islet β cell function in a Chinese population with different degrees of … doi:10.1002
Nutrition Journal Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study Pubmed:27071648
Pharmacological reports The Role of PON-1, GR, IL-18, and oxLDL in Depression With and Without Posttraumatic Stress Disorder science:article
Pharmacological Reports The role of PON-1, GR, IL-18, and OxLDL in depression with and without posttraumatic stress disorder. pubmed:28623707
Canadian journal of physiology and pharmacology Ambroxol attenuates cisplatin-induced hepato and nephrotoxicity via inhibition of p-JNK/p-ERK Pubmed: 30383980
FREE RADICAL RESEARCH Negative association between antioxidant vitamin intake and non-alcoholic fatty liver disease in Chinese non-diabetic adults: mediation models involving superoxide … Pubmed: 32985285
Lipids Health Dis Triglyceride is independently correlated with insulin resistance and islet beta cell function: a study in population with different glucose and lipid metabolism … Pubmed: 32487177
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY Potential Protective Effect of Dietary Intake of Non-α-Tocopherols on Cellular Aging Markers Mediated by Tumor Necrosis Factor-α in Prediabetes: A Cross … Pubmed: 32509152
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY TNFα Mediates the Interaction of Telomeres and Mitochondria Induced by Hyperglycemia: A Rural Community-Based Cross-Sectional Study Pubmed: 32454945
oxidative medine cellular longevity Relationship between Decreased Serum Superoxide Dismutase Activity and Metabolic Syndrome: Synergistic Mediating Role of Insulin Resistance and β … Pubmed: 32617139
The Journal of Clinical Endocrinology & Metabolism High Hemoglobin glycation index is associated with telomere attrition independent of HbA1c, mediating by TNFα 34562085
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPB314Ra01 Recombinant Glutathione Reductase (GR) Positive Control; Immunogen; SDS-PAGE; WB.
PAB314Ra01 Polyclonal Antibody to Glutathione Reductase (GR) WB; IHC; ICC; IP.
MAB314Ra21 Monoclonal Antibody to Glutathione Reductase (GR) WB; IHC; ICC; IP.
SEB314Ra ELISA Kit for Glutathione Reductase (GR) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB314Ra Multiplex Assay Kit for Glutathione Reductase (GR) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.