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Monoclonal Antibody to Cluster Of Differentiation 42b (CD42b)

GP1Ba; CD42-B; CD42b-Alpha; GP1-BA; BSS; GP1B; GPIBA; Glycocalicin; Glycoprotein Ib Alpha Polypeptide, Platelet

SPECIFITY

The antibody is a mouse monoclonal antibody raised against CD42b. It has been selected for its ability to recognize CD42b in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Scientific Reports Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIb β expression articles:s41598-017-08975-y
Platelets Actin polymerization regulates glycoprotein Ib¦Á shedding 33979555
Cell Death & Disease Essential role of zyxin in platelet biogenesis and glycoprotein Ib-IX surface expression 34657146
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