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Monoclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4)

CD184; Fusin; NPYR; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYRL; WHIM; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide-associated protein 3

  • Product No.MAA940Hu21
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)D4
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 102  US$ 239  US$ 341  US$ 853  US$ 3410 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against CXCR4. It has been selected for its ability to recognize CXCR4 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
International Journal of Cancer Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model Wiley: source
Plos one Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma PubMed: PMC3589458
Atherosclerosis The non-alcoholic fraction of beer increases stromal cell derived factor 1 and the number of circulating endothelial progenitor cells in high cardiovascular risk subjects: A randomized clinical trial Pubmed:24530788
Pharmacol Rep.? Comparison of chemokines (CCL-5 and SDF-1), chemokine receptors (CCR-5 and CXCR-4) and IL-6 levels in patients with different severities of depression Pubmed:25150002
Pharmacological Reports Serum concentrations of chemokines (CCL-5 and CXCL-12), chemokine receptors (CCR-5 and CXCR-4), and IL-6 in patients with posttraumatic stress disorder and avoidant personality disorder PubMed: 26481549
Pharmacological Reports A study of chemokines, chemokine receptors and interleukin-6 in patients with panic disorder, personality disorders and their co-morbidity Pubmed:27208878
BMC Cancer.  Enhancement of the CXCL12/CXCR4 axis due to acquisition of gemcitabine resistance in pancreatic cancer: effect of CXCR4 antagonists pmc:PMC4866076
Frontiers in Bioengineering and Biotechnology Matrix Metalloproteinase-2 Impairs Homing of Intracoronary Delivered Mesenchymal Stem Cells in a Porcine Reperfused Myocardial Infarction: Comparison … Pubmed:29670878
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA940Hu01 Recombinant Chemokine C-X-C-Motif Receptor 4 (CXCR4) Positive Control; Immunogen; SDS-PAGE; WB.
CPA940Hu21 OVA Conjugated Chemokine C-X-C-Motif Receptor 4 (CXCR4) Immunogen; SDS-PAGE; WB.
PAA940Hu08 Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) WB; IHC; ICC; IP.
PAA940Hu01 Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) WB; IHC; ICC; IP.
FAA940Hu01 Anti-Chemokine C-X-C-Motif Receptor 4 (CXCR4) Polyclonal Antibody Flow cytometry.
FAA940Hu41 PE-Linked Anti-Chemokine C-X-C-Motif Receptor 4 (CXCR4) Polyclonal Antibody Flow cytometry.
FAA940Hu51 APC-Linked Anti-Chemokine C-X-C-Motif Receptor 4 (CXCR4) Polyclonal Antibody Flow cytometry.
FAA940Hu81 FITC-Linked Anti-Chemokine C-X-C-Motif Receptor 4 (CXCR4) Polyclonal Antibody Flow cytometry.
MAA940Hu21 Monoclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) WB; IHC; ICC; IP.
MAA940Hu22 Monoclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) WB; IHC; ICC; IP.
RAA940Hu21 Recombinant Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) WB; IF; ICC; IHC; IP; FCM.
SEA940Hu ELISA Kit for Chemokine C-X-C-Motif Receptor 4 (CXCR4) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA940Hu Multiplex Assay Kit for Chemokine C-X-C-Motif Receptor 4 (CXCR4) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.