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Rat Model for White Matter Injury (WMI)

Brain white matter damage;

  • Product No.DSI731Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceInduced by ischemia-hypoxia
  • Model Animal StrainsNeonatal SD rats (SPF), 3 days old
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period3 weeks
  • Modeling Method1. SD rats inhalation anesthesia with ether, supine position,after the iodophor disinfection, under the microscope in the neck to the right side of the trachea 0.5~1.0 cm longitudinal incision. The right common carotid artery was ligated with 7/0 suture line, and the artery was cut between the two ends of the ligation to prevent the ligation line from falling out, then suturing the incision, the epidermis was washed with normal saline.
    2. After the operation, the newborn rats were placed in the hypoxic chamber 2 hours (n = 92% and the mixture of 8% oxygen). After the completion of the operation, return to the maternal side feeding.
  • ApplicationsDisease Model
  • Downloadn/a
  • UOM Each case
  • FOB US$ 260 
    For more details, please contact local distributors!

Model Evaluation

Pathological Results

Cytokines Level

Statistical Analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
DSI731Ra01 Rat Model for White Matter Injury (WMI) Disease Model