3C-like proteinase, SARS-CoV-2 (3CLP)
[Edit]3CL Protease; 3CL Proteinase; 3C-like main protease; 3CL-Mpro; COVID-19; M Proteinase; Main Protease; Mpro
![3C-like proteinase, SARS-CoV-2 (3CLP)](/upload/item/img/3C-like-proteinase--SARS-CoV-2-(3CLP)-X353.png)
The 3CL protease from the human SARS-CoV-2 coronavirus is highly conserved cysteine hydrolases in β-coronaviruses. It plays an indispensable role in transcription and replication of viral RNAs and has been recognized as key targets for preventing and treating coronavirus-caused infectious diseases, including COVID-19. 3CL protease is located within the non-structural proteins 3 (NS3) section of the viral polypeptide. As a matured protein in a dimeric form, generally, the monomer of 3CLpro is a transient state that proved to be enzymatically less active, while the dimeric form acts as a functional unit with the highest hydrolytic activity. Considering that 3CLpros play a vital role in CoV replication, especially in SARS‐CoV‐2 and SARS‐CoV, these key hydrolases have been validated as promising targets for developing broad‐spectrum anti‐CoV agents.
Organism species: Pan-species (General)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant 3C-like proteinase, SARS-CoV-2 (3CLP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to 3C-like proteinase, SARS-CoV-2 (3CLP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to 3C-like proteinase, SARS-CoV-2 (3CLP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for 3C-like proteinase, SARS-CoV-2 (3CLP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for 3C-like proteinase, SARS-CoV-2 (3CLP) | ELISA Kit Customized Service Offer |