![Insulin-2 (Ins2)](/upload/item/img/Insulin-2-(Ins2)-X330.png)
One functional neuroendocrine tumor that causes hypoglycemia due to inappropriately high insulin production is an insulinoma. In rats, two genes coding for insulin, insulin 1 (Ins1) and insulin 2 (Ins2) are found on chromosome 1. Ins1 was produced from an Ins2 transcript, and it was inserted into the genome via an RNA-mediated duplication-transposition event, according to some structural feature analyses.Mature insulin,consisting of two polypeptide chains,B and A, connected by two disulfide bridges, is the end product of the maturation of preproinsulin, a single precursor polypeptide chain of 110 amino acids. Ins2 and Ins1 are expressed in the pancreas and both encode proinsulin peptides composed of four parts: signal peptide, B chain, C-peptide, and A chain. Ins2 increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Insulin-2 (Ins2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Insulin-2 (Ins2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Insulin-2 (Ins2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Insulin-2 (Ins2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Insulin-2 (Ins2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Insulin-2 (Ins2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Insulin-2 (Ins2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Insulin-2 (Ins2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Insulin-2 (Ins2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Insulin-2 (Ins2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Insulin-2 (Ins2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Insulin-2 (Ins2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Insulin-2 (Ins2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Insulin-2 (Ins2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Insulin-2 (Ins2) | ELISA Kit Customized Service Offer |