![Chromosome 9 Open Reading Frame 69 (C9orf69)](/upload/item/img/Chromosome-9-Open-Reading-Frame-69-(C9orf69)-W974.gif)
Chromosome 9 is highly structurally polymorphic. It contains the largest autosomal block of heterochromatin, which is heteromorphic in 6-8% of humans, whereas pericentric inversions occur in more than 1% of the population. The finished euchromatic sequence of chromosome 9 comprises 109,044,351 base pairs and represents >99.6% of the region. Analysis of the sequence reveals many intra- and interchromosomal duplications, including segmental duplications adjacent to both the centromere and the large heterochromatic block. We have annotated 1,149 genes, including genes implicated in male-to-female sex reversal, cancer and neurodegenerative disease, and 426 pseudogenes. The chromosome contains the largest interferon gene cluster in the human genome. There is also a region of exceptionally high gene and G + C content including genes paralogous to those in the major histocompatibility complex.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Chromosome 9 Open Reading Frame 69 (C9orf69) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Chromosome 9 Open Reading Frame 69 (C9orf69) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Chromosome 9 Open Reading Frame 69 (C9orf69) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Chromosome 9 Open Reading Frame 69 (C9orf69) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Chromosome 9 Open Reading Frame 69 (C9orf69) | ELISA Kit Customized Service Offer |
- "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Host cell protein C9orf9 promotes viral proliferation via interaction with HSV-1 UL25 protein."Zhongguo Bing Du Xue 26:171-180(2011) [PubMed] [Europe PMC] [Abstract]