![Jagunal Homolog 1 (JAGN1)](/upload/item/img/Jagunal-Homolog-1-(JAGN1)-70856.gif)
JAGN1 Belongs to the jagunal family.Vesicular traffic in the Drosophila melanogaster oocyte occurs actively during vitellogenesis. ER becomes concentrated into subcortical clusters during vitellogenesis. This ER reorganization requires Jagunal, which is an evolutionarily conserved ER membrane protein. Loss of Jagunal reduces vesicular traffic to the oocyte lateral membrane, but does not affect posterior polarized vesicular traffic, suggesting a role for Jagunal in facilitating vesicular traffic in the subcortex. Reduced membrane traffi c caused by loss of Jagunal affects oocyte and bristle growth. ER reorganization is an important mechanism used by cells to prepare for an increased demand for membrane traffic, and Jagunal facilitates this process through ER clustering.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Jagunal Homolog 1 (JAGN1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Jagunal Homolog 1 (JAGN1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Jagunal Homolog 1 (JAGN1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Jagunal Homolog 1 (JAGN1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Jagunal Homolog 1 (JAGN1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Jagunal Homolog 1 (JAGN1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Jagunal Homolog 1 (JAGN1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Jagunal Homolog 1 (JAGN1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Jagunal Homolog 1 (JAGN1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Jagunal Homolog 1 (JAGN1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Jagunal Homolog 1 (JAGN1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Jagunal Homolog 1 (JAGN1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Jagunal Homolog 1 (JAGN1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Jagunal Homolog 1 (JAGN1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Jagunal Homolog 1 (JAGN1) | ELISA Kit Customized Service Offer |
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- "JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia." Nat. Genet. 46:1021-1027(2014) [PubMed] [Europe PMC] [Abstract]