Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP)
[Edit]ACAM; ASAM; Adipocyte Adhesion Molecule; Adipocyte-Specific Adhesion Molecule; CXADR Like Membrane Protein
![Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP)](/upload/item/img/Coxsackie-And-Adenovirus-Receptor-Like-Membrane-Protein-(CLMP)-70786.gif)
CLMP is composed of 373 amino acids including an extracellular part containing a V- and a C2-type domain, a transmembrane region and a cytoplasmic tail. CLMP mRNA was detected in a variety of both human and mouse tissues and cell lines. The protein migrated with an Mr of around 48 on SDS-PAGE and was predominantly expressed in epithelial cells within different tissues. In cultured epithelial cells, CLMP was detected in areas of cell-cell contacts. When exogenously expressed in polarized MDCK cells, CLMP was restricted to the subapical area of the lateral cell surface, where it co-localized with the tight junction markers ZO-1 and occludin. Also endogenous CLMP showed association with tight junctions, as analyzed in polarized human CACO-2 cells.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPW786Hu01 | Recombinant Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW786Hu21 | Monoclonal Antibody to Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | WB; IHC; ICC; IP. |
PAW786Hu01 | Polyclonal Antibody to Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | WB | |
Assay Kits | SEW786Hu | ELISA Kit for Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Coxsackie And Adenovirus Receptor Like Membrane Protein (CLMP) | ELISA Kit Customized Service Offer |
- "Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity."Biochem. J. 387:343-353(2005) [PubMed] [Europe PMC] [Abstract]
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "CLMP, a novel member of the CTX family and a new component of epithelial tight junctions."J. Biol. Chem. 279:796-804(2004) [PubMed] [Europe PMC] [Abstract]
- "CLMP is required for intestinal development, and loss-of-function mutations cause congenital short-bowel syndrome." Gastroenterology 142:453-462(2012) [PubMed] [Europe PMC] [Abstract]