≡

Lysine Rich Nucleolar Protein 1 (KNOP1)

[Edit]

TSG118; FAM191A; C16orf88; Chromosome 16 Open Reading Frame 88; Testis Specific Gene 118

Lysine Rich Nucleolar Protein 1 (KNOP1)
CCC W708
HGNC 34404
MGI 1913606
PubMed 15833274
RGD 1565096
UniProt Q1ED39
The nucleolar association of ZFP106 did neither require ongoing ribosomal RNA synthesis nor nucleolar chromatin indicating that a protein-protein interaction confines ZFP106 to the nucleolus. Deletion analysis revealed that the C-terminal WD40 repeat region functions in nucleolar targeting. This domain interacts with the product of testis-specific gene 118 (TSG118), which also co-localizes with ZFP106 in the nucleolus.
Rapid downregulation of TSG118 expression during in vitro terminal differentiation coincides with a loss of nucleolar ZFP106. By its structural features and expression, TSG118 mimics nucleostemin, a nucleolar protein linked to the proliferation potential of stem cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysine Rich Nucleolar Protein 1 (KNOP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysine Rich Nucleolar Protein 1 (KNOP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysine Rich Nucleolar Protein 1 (KNOP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysine Rich Nucleolar Protein 1 (KNOP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysine Rich Nucleolar Protein 1 (KNOP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysine Rich Nucleolar Protein 1 (KNOP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysine Rich Nucleolar Protein 1 (KNOP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysine Rich Nucleolar Protein 1 (KNOP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysine Rich Nucleolar Protein 1 (KNOP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysine Rich Nucleolar Protein 1 (KNOP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysine Rich Nucleolar Protein 1 (KNOP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysine Rich Nucleolar Protein 1 (KNOP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysine Rich Nucleolar Protein 1 (KNOP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysine Rich Nucleolar Protein 1 (KNOP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysine Rich Nucleolar Protein 1 (KNOP1) ELISA Kit Customized Service Offer
  1. "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q."Genomics 60:295-308(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction."Mol. Cell. Proteomics 6:1952-1967(2007) [PubMed] [Europe PMC] [Abstract]
  4. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]