Zinc Finger, BED-Type Containing Protein 8 (ZBED8)

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Buster3; C5orf54; Transposon-Derived Buster3 Transposase-Like Protein; Chromosome 5 Open Reading Frame 54

Zinc Finger, BED-Type Containing Protein 8 (ZBED8)
Changes in the structure of chromosome 5 are associated with certain forms of cancer and conditions related to cancer. These changes are typically somatic, which means they are acquired during a person's lifetime and are present only in tumor cells. Deletions in the long (q) arm of the chromosome have been identified in a form of blood cancer known as acute myeloid leukemia (AML). These deletions also frequently occur in a disorder called myelodysplastic syndrome, which is a disease of the blood and bone marrow. People with this condition have a low number of red blood cells (anemia) and an increased risk of developing AML. When myelodysplastic syndrome is associated with a specific deletion in the long arm of chromosome 5, it is known as 5q- (5q minus) syndrome.Studies suggest that some genes on chromosome 5 play critical roles in the growth and division of cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger, BED-Type Containing Protein 8 (ZBED8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger, BED-Type Containing Protein 8 (ZBED8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger, BED-Type Containing Protein 8 (ZBED8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger, BED-Type Containing Protein 8 (ZBED8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger, BED-Type Containing Protein 8 (ZBED8) ELISA Kit Customized Service Offer
  1. "Interspersed repeats and other mementos of transposable elements in mammalian genomes."Curr. Opin. Genet. Dev. 9:657-663(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions."PLoS ONE 8:E59940-E59940(2013) [PubMed] [Europe PMC] [Abstract]