CRHR1 Intronic Transcript 1 (CRHR1IT1)

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C17orf69; CRHR1-IT1; Chromosome 17 Open Reading Frame 69

CRHR1 Intronic Transcript 1 (CRHR1IT1)
Chromosome 17 is unusual among the human chromosomes in many respects. It is the largest human autosome with orthology to only a single mouse chromosome1, mapping entirely to the distal half of mouse chromosome 11. Chromosome 17 is rich in protein-coding genes, having the second highest gene density in the genome2, 3. It is also enriched in segmental duplications, ranking third in density among the autosomes4. Comparison of the orthologous regions reveals striking differences. In contrast to the typical pattern seen in mammalian evolution5, 6, the human sequence has undergone extensive intrachromosomal rearrangement, whereas the mouse sequence has been remarkably stable. Moreover, although the human sequence has a high density of segmental duplication, the mouse sequence has a very low density.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CRHR1 Intronic Transcript 1 (CRHR1IT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CRHR1 Intronic Transcript 1 (CRHR1IT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CRHR1 Intronic Transcript 1 (CRHR1IT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CRHR1 Intronic Transcript 1 (CRHR1IT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for CRHR1 Intronic Transcript 1 (CRHR1IT1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]