Chromosome 1 Open Reading Frame 123 (C1orf123)

The C1orf123 protein is 160 amino acids in length and weighs 18.0 kdal. The C1orf123 protein has no transmembrane regions so is therefore likely not a transmembrane protein. Three post-translational modification sites have been experiementally found, including a phosphotyrosine, phosphoserine, and glycyl-lysine isopeptide.[9] A portion of the 3' UTR of C1orf123 has 100% identity with the mRNA for Homo sapiens carnitine palmityoyltransferase 2 is a nuclear gene that encodes mitochondrial protein. This gene works with carnitine palmitoyltransferase I, and the encoded protein oxidizes long-chain fatty acids in the mitochondria. C1orf123 protein secondary structure has been found to be very similar to that of MAL13P1.257 protein.