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KRI1 Homolog (KRI1)

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KRI1 Homolog (KRI1)
CCC W204
HGNC 25769
MGI 2384899
PubMed 11027267
UniProt Q8N9T8
KRI1 overlaps with the gene for cysteine endopeptidase AUT-like 4 in a head-to-tail orientation. In C. elegans, removing the germ cells extends life span by triggering the nuclear localization and activation of the DAF-16/FOXO transcription factor in the intestine. The reproductive system communicates with the intestine through lipophilic-hormone signaling and that a gene called kri-1 is likely to act in the intestine to promote DAF-16 nuclear localization in response to this signal. This lipophilicsignaling pathway and kri-1 are not required for DAF-16’s nuclear localization and life-span extension in animals with decreased insulin/IGF-1 signaling. Thus, this pathway specifically enables the integration of cues from the reproductive system with central DAF-16-activation pathways to influence the aging of the animal.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant KRI1 Homolog (KRI1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to KRI1 Homolog (KRI1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to KRI1 Homolog (KRI1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for KRI1 Homolog (KRI1) CLIA Kit Customized Service Offer
n/a ELISA Kit for KRI1 Homolog (KRI1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant KRI1 Homolog (KRI1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to KRI1 Homolog (KRI1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to KRI1 Homolog (KRI1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for KRI1 Homolog (KRI1) CLIA Kit Customized Service Offer
n/a ELISA Kit for KRI1 Homolog (KRI1) ELISA Kit Customized Service Offer
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