Chromosome 3 Open Reading Frame 14 (C3orf14)

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Chromosome 3 Open Reading Frame 14 (C3orf14)
C3orf14 is a gene of uncertain function located at 3p14.2 near fragile site FRBA3—which falls between this gene and the centromere. Its protein is expected to localize to the nucleus and bind DNA. This gene was first identified in the hypothalamic-pituitary-adrenal axis (HPA axis). The GEO and EST profiles in NCBI, indicate that its expression level varies from tissue to tissue; however its reported expression is 1.2 times that of the average gene. It has highest expression in the pancreas and nervous tissue (in humans). It is underexpressed in many cancer cell lines, however this may be due to its close proximity to the tumor suppressor gene FHIT, and the chromosomal fragile site FRBA3. Breakage at this site inactivates FHIT and can lead to the loss of C3orf14.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromosome 3 Open Reading Frame 14 (C3orf14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromosome 3 Open Reading Frame 14 (C3orf14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromosome 3 Open Reading Frame 14 (C3orf14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromosome 3 Open Reading Frame 14 (C3orf14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromosome 3 Open Reading Frame 14 (C3orf14) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromosome 3 Open Reading Frame 14 (C3orf14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromosome 3 Open Reading Frame 14 (C3orf14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromosome 3 Open Reading Frame 14 (C3orf14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromosome 3 Open Reading Frame 14 (C3orf14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromosome 3 Open Reading Frame 14 (C3orf14) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromosome 3 Open Reading Frame 14 (C3orf14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromosome 3 Open Reading Frame 14 (C3orf14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromosome 3 Open Reading Frame 14 (C3orf14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromosome 3 Open Reading Frame 14 (C3orf14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromosome 3 Open Reading Frame 14 (C3orf14) ELISA Kit Customized Service Offer
  1. "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning." Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]