DEAD Box Polypeptide 53 (DDX53)
[Edit]CAGE; CT26; Cancer Associated Gene; Cancer/Testis Atigen 26; Asp-Glu-Ala-Asp Box Polypeptide 53; Probable ATP-dependent RNA helicase DDX53
![DEAD Box Polypeptide 53 (DDX53)](/upload/item/img/DEAD-Box-Polypeptide-53-(DDX53)-89486.gif)
DDX53 Expressed in testis. Wide expression in various cancer tissues and cancer cell lines. Belongs to the DEAD box helicase family.Contains 1 helicase ATP-binding domain.Contains 1 helicase C-terminal domain.Contains 1 KH domain.This intronless gene encodes a protein which contains several domains found in members of the DEAD-box helicase protein family. Other members of this protein family participate in ATP-dependent RNA unwinding.
DEAD box proteins are involved in an assortment of metabolic processes that involve RNA. They are highly conserved in nine domains and can be found in both prokaryotes and eukaryotes, but not all. Many organisms, including humans, contain DEAD-box helicases, which are involved in RNA metabolism.these proteins involved in RNA metabolism had several common elements.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant DEAD Box Polypeptide 53 (DDX53) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to DEAD Box Polypeptide 53 (DDX53) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to DEAD Box Polypeptide 53 (DDX53) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for DEAD Box Polypeptide 53 (DDX53) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for DEAD Box Polypeptide 53 (DDX53) | ELISA Kit Customized Service Offer |
- "Identification and characterization of a novel cancer/testis antigen gene CAGE."Biochem. Biophys. Res. Commun. 292:715-726(2002) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Comparative structural analysis of human DEAD-box RNA helicases."PLoS ONE 5:E12791-E12791(2010) [PubMed] [Europe PMC] [Abstract]
- "Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma." Nature 469:539-542(2011) [PubMed] [Europe PMC] [Abstract]