Mitochondrial Genome Maintenance Exonuclease 1 (MGME1)

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DDK1; C20orf72

Mitochondrial Genome Maintenance Exonuclease 1 (MGME1)
Chromosome 20 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 20 spans around 63 million base pairs (the building material of DNA) and represents between 2 and 2.5 percent of the total DNA in cells. Chromosome 20 was fully sequenced in 2001 and contained 59,187,298 base pairs representing 99.4% of the euchromatic DNA.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 20 contains over 900 genes. New discoveries have recently linked this chromosome to the increasing susceptibility to male-pattern baldness.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  5. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease." Nat. Genet. 45:214-219(2013) [PubMed] [Europe PMC] [Abstract]
  8. "Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels."Nucleic Acids Res. 41:3144-3161(2013) [PubMed] [Europe PMC] [Abstract]