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Pore Membrane Protein of 121kDa C (POM121C)

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Nuclear pore membrane protein 121-2; Nuclear envelope pore membrane protein POM 121C

Pore Membrane Protein of 121kDa C (POM121C)
CCC V247
HGNC 34005
UniProt A8CG34
POM121C Belongs to the POM121 family.Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).
POM121 encodes a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is an integral membrane protein that localizes to the central spoke ring complex and participates in anchoring the nuclear pore complex to the nuclear envelope. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pore Membrane Protein of 121kDa C (POM121C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pore Membrane Protein of 121kDa C (POM121C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pore Membrane Protein of 121kDa C (POM121C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pore Membrane Protein of 121kDa C (POM121C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pore Membrane Protein of 121kDa C (POM121C) ELISA Kit Customized Service Offer
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  3. "Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes."FEBS Lett. 581:4910-4916(2007) [PubMed] [Europe PMC] [Abstract]
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  8. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]