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Seizure Threshold Protein 2 (SZT2)

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SZT2A; SZT2B; C1orf84

Seizure Threshold Protein 2 (SZT2)
CCC U874
HGNC 29040
MGI 3033336
PubMed 23932106
RGD 1308616
UniProt Q5T011
Wiki SZT2
SZT2 is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. Mutations in this gene have been shown to cause infantile encephalopathy with epilepsy and dysmorphic corpus callosum.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Seizure Threshold Protein 2 (SZT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Seizure Threshold Protein 2 (SZT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Seizure Threshold Protein 2 (SZT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Seizure Threshold Protein 2 (SZT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Seizure Threshold Protein 2 (SZT2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Seizure Threshold Protein 2 (SZT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Seizure Threshold Protein 2 (SZT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Seizure Threshold Protein 2 (SZT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Seizure Threshold Protein 2 (SZT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Seizure Threshold Protein 2 (SZT2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Seizure Threshold Protein 2 (SZT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Seizure Threshold Protein 2 (SZT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Seizure Threshold Protein 2 (SZT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Seizure Threshold Protein 2 (SZT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Seizure Threshold Protein 2 (SZT2) ELISA Kit Customized Service Offer
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  8. "A novel giant peroxisomal superoxide dismutase motif-containing protein."Free Radic. Biol. Med. 48:811-820(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Biallelic SZT2 mutations cause infantile encephalopathy with epilepsy and dysmorphic corpus callosum." Am. J. Hum. Genet. 93:524-529(2013) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]