Myelin Associated Neurite Outgrowth Inhibitor (MANI)

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FAM168B; p20; Family With Sequence Similarity 168, Member B

Myelin Associated Neurite Outgrowth Inhibitor (MANI)
FAM168B Belongs to the FAM168 subfamily. a transmembrane protein (TP) is a protein that goes from one side of a membrane through to the other side of the membrane. Many TPs function as gateways or "loading docks" to deny or permit the transport of specific substances across the biological membrane, to get into the cell, or out of the cell as in the case of waste byproducts. As a response to the shape of certain molecules these "freight handling" TPs may have special ways of folding up or bending that will move a substance through the biological membrane.A transmembrane protein is a polytopic protein that spans an entire biological membrane. Transmembrane proteins aggregate and precipitate in water. They require detergents or nonpolar solvents for extraction, although some of them (beta-barrels) can be also extracted using denaturing agents.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myelin Associated Neurite Outgrowth Inhibitor (MANI) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myelin Associated Neurite Outgrowth Inhibitor (MANI) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myelin Associated Neurite Outgrowth Inhibitor (MANI) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myelin Associated Neurite Outgrowth Inhibitor (MANI) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myelin Associated Neurite Outgrowth Inhibitor (MANI) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myelin Associated Neurite Outgrowth Inhibitor (MANI) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myelin Associated Neurite Outgrowth Inhibitor (MANI) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myelin Associated Neurite Outgrowth Inhibitor (MANI) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myelin Associated Neurite Outgrowth Inhibitor (MANI) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myelin Associated Neurite Outgrowth Inhibitor (MANI) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myelin Associated Neurite Outgrowth Inhibitor (MANI) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myelin Associated Neurite Outgrowth Inhibitor (MANI) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myelin Associated Neurite Outgrowth Inhibitor (MANI) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myelin Associated Neurite Outgrowth Inhibitor (MANI) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myelin Associated Neurite Outgrowth Inhibitor (MANI) ELISA Kit Customized Service Offer
  1. "The novel protein MANI modulates neurogenesis and neurite-cone growth."J. Cell. Mol. Med. 15:1713-1725(2011) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  4. "Characterizing the neurite outgrowth inhibitory effect of Mani."FEBS Lett. 586:3018-3023(2012) [PubMed] [Europe PMC] [Abstract]