Tripartite Motif Family Like Protein 2 (TRIML2)

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SPRYD6; SPRY Domain Containing Protein 6; Probable E3 ubiquitin-protein ligase TRIML2

Tripartite Motif Family Like Protein 2 (TRIML2)
TRIML2 Contains 1 B30.2/SPRY domain.The B30.2/SPRY domain is present in 700 eukaryotic (150 human) proteins, including medically important proteins such as TRIM5 and Pyrin. Nonetheless, the functional role of this modular domain remained unclear. One end of the -sandwich as the surface interacting with an RNA helicase VASA with a 40 nM dissociation constant. The sequence variation in TRIM5 responsible for HIV-1 restriction and most of the mutations in Pyrin causing familial Mediterranean fever map on this surface, implicating the corresponding region in many B30.2/SPRY domains as the ligand-binding site. The amino acids lining the binding surface are highly variable among the B30.2/SPRY domains, suggesting that these domains are protein-interacting modules, which recognize a specific individual partner protein rather than a consensus sequence motif.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tripartite Motif Family Like Protein 2 (TRIML2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tripartite Motif Family Like Protein 2 (TRIML2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tripartite Motif Family Like Protein 2 (TRIML2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tripartite Motif Family Like Protein 2 (TRIML2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tripartite Motif Family Like Protein 2 (TRIML2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tripartite Motif Family Like Protein 2 (TRIML2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tripartite Motif Family Like Protein 2 (TRIML2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tripartite Motif Family Like Protein 2 (TRIML2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tripartite Motif Family Like Protein 2 (TRIML2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tripartite Motif Family Like Protein 2 (TRIML2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tripartite Motif Family Like Protein 2 (TRIML2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tripartite Motif Family Like Protein 2 (TRIML2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tripartite Motif Family Like Protein 2 (TRIML2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tripartite Motif Family Like Protein 2 (TRIML2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tripartite Motif Family Like Protein 2 (TRIML2) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]