ENTH Domain Containing Protein 1 (ENTHD1)

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Epsin-2B

ENTH Domain Containing Protein 1 (ENTHD1)
ENTHD1 Contains 1 ENTH (epsin N-terminal homology) domain.Epsins are endocytic proteins with a structured epsin N-terminal homology (ENTH) domain that binds phosphoinositides and a poorly structured C-terminal region that interacts with ubiquitin and endocytic machinery, including clathrin and endocytic scaffolding proteins. Yeast has two redundant genes encoding epsins, ENT1 and ENT2; deleting both genes is lethal. Mutational analysis of the ENTH domain revealed a surface patch that is essential for viability and that binds guanine nucleotide triphosphatase-activating proteins for Cdc42, a critical regulator of cell polarity in all eukaryotes. Furthermore, the epsins contribute to regulation of specific Cdc42 signaling pathways in yeast cells. These data support a model in which the epsins function as spatial and temporal coordinators of endocytosis and cell polarity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ENTH Domain Containing Protein 1 (ENTHD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ENTH Domain Containing Protein 1 (ENTHD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ENTH Domain Containing Protein 1 (ENTHD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ENTH Domain Containing Protein 1 (ENTHD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for ENTH Domain Containing Protein 1 (ENTHD1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ENTH Domain Containing Protein 1 (ENTHD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ENTH Domain Containing Protein 1 (ENTHD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ENTH Domain Containing Protein 1 (ENTHD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ENTH Domain Containing Protein 1 (ENTHD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for ENTH Domain Containing Protein 1 (ENTHD1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ENTH Domain Containing Protein 1 (ENTHD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ENTH Domain Containing Protein 1 (ENTHD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ENTH Domain Containing Protein 1 (ENTHD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ENTH Domain Containing Protein 1 (ENTHD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for ENTH Domain Containing Protein 1 (ENTHD1) ELISA Kit Customized Service Offer
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  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]