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Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3)

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AH2; Annealing helicase 2; DNA annealing helicase and endonuclease ZRANB3; DNA annealing helicase ZRANB3; Endonuclease ZRANB3

Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3)
CCC U256
HGNC 25249
MGI 1918362
PubMed 22705370
UniProt Q5FWF4
ZRANB3 Belongs to the SNF2/RAD54 helicase family.Contains 1 helicase ATP-binding domain.Contains 1 helicase C-terminal domain.Contains 1 RanBP2-type zinc finger.THE SNF2/RAD54 family proteins are components of ATP-dependent chromatin-remodeling complexes involved in transcription and/or DNA repair. Within the SNF2/RAD54 family, the CHD (chromodomain-helicase-DNA-binding) group all contain CHROMO (chromatin organization modifier) domains, which interact with methylated lysines in the N-terminal tails of histones. The CHD group can be further divided into at least three classes on the basis of the presence or absence of two other protein domains. The CHD1 class proteins have only the SNF2/RAD54 ATPase domain and CHROMO domains.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Ran Binding Domain Containing Protein 3 (ZRANB3) ELISA Kit Customized Service Offer
  1. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Annealing helicase 2 (AH2), a DNA-rewinding motor with an HNH motif."Proc. Natl. Acad. Sci. U.S.A. 107:20970-20973(2010) [PubMed] [Europe PMC] [Abstract]
  8. "ZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress response."Genes Dev. 26:1558-1572(2012) [PubMed] [Europe PMC] [Abstract]
  9. "The HARP-like domain-containing protein AH2/ZRANB3 binds to PCNA and participates in cellular response to replication stress."Mol. Cell 47:410-421(2012) [PubMed] [Europe PMC] [Abstract]
  10. "Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress."Mol. Cell 47:396-409(2012) [PubMed] [Europe PMC] [Abstract]