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Ring Finger Protein 144 (RNF144)

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UBCE7IP4; RNF144A; UbcM4-interacting protein 4; Ubiquitin-conjugating enzyme 7-interacting protein 4; E3 ubiquitin-protein ligase RNF144A

Ring Finger Protein 144 (RNF144)
CCC U001
HGNC 20457
MGI 1344401
PubMed 23382809
RGD 1561737
UniProt P50876
RNF144 contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The mouse counterpart of this protein has been shown to interact with Ube2l3/UbcM4, which is an ubiquitin-conjugating enzyme involved in embryonic development.
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Lacks the His residue in the RING-type domain 2 that is one of the conserved features of the family.A RING (Really Interesting New Gene) finger domain is a protein structural domain of zinc finger type which contains a Cys3HisCys4 amino acid motif which binds two zinc cations.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ring Finger Protein 144 (RNF144) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ring Finger Protein 144 (RNF144) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ring Finger Protein 144 (RNF144) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ring Finger Protein 144 (RNF144) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ring Finger Protein 144 (RNF144) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ring Finger Protein 144 (RNF144) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ring Finger Protein 144 (RNF144) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ring Finger Protein 144 (RNF144) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ring Finger Protein 144 (RNF144) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ring Finger Protein 144 (RNF144) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ring Finger Protein 144 (RNF144) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ring Finger Protein 144 (RNF144) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ring Finger Protein 144 (RNF144) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ring Finger Protein 144 (RNF144) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ring Finger Protein 144 (RNF144) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 3:17-24(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4."FEBS Lett. 454:257-261(1999) [PubMed] [Europe PMC] [Abstract]
  5. "RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage."Proc. Natl. Acad. Sci. U.S.A. 111:E2646-E2655(2014) [PubMed] [Europe PMC] [Abstract]
  6. "Solution structure of the RING finger domain of the human UbcM4-interacting protein 4."Submitted (NOV-2004) to the PDB data bank