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NCU-G1 is a highly glycosylated integral membrane protein of the lysosome. It is localized on chromosome 1 and consists of 6 exons. Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator.
NCU-G1 encodes a 404 amino acid protein with a calculated molecular mass of 39 kDa. NCU-G1 was found to be a highly conserved nuclear protein rich in proline with a molecular weight of approximately 44 kDa.Its lysosomal localization was confirmed using immunofluorescence with a C-terminally His-tagged NCU-G1 and the lysosomal marker LAMP-1 as a reference, and by subcellular fractionation of mouse liver after a tyloxapol-induced density shift of the lysosomal fraction using an anti-NCU-G1 antiserum.
NCU-G1 encodes a 404 amino acid protein with a calculated molecular mass of 39 kDa. NCU-G1 was found to be a highly conserved nuclear protein rich in proline with a molecular weight of approximately 44 kDa.Its lysosomal localization was confirmed using immunofluorescence with a C-terminally His-tagged NCU-G1 and the lysosomal marker LAMP-1 as a reference, and by subcellular fractionation of mouse liver after a tyloxapol-induced density shift of the lysosomal fraction using an anti-NCU-G1 antiserum.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Glycosylated Lysosomal Membrane Protein (GLMP) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Glycosylated Lysosomal Membrane Protein (GLMP) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Glycosylated Lysosomal Membrane Protein (GLMP) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Glycosylated Lysosomal Membrane Protein (GLMP) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Glycosylated Lysosomal Membrane Protein (GLMP) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPT758Mu01 | Recombinant Glycosylated Lysosomal Membrane Protein (GLMP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPT758Mu02 | Recombinant Glycosylated Lysosomal Membrane Protein (GLMP) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAT758Mu01 | Polyclonal Antibody to Glycosylated Lysosomal Membrane Protein (GLMP) | WB; IHC |
| PAT758Mu02 | Polyclonal Antibody to Glycosylated Lysosomal Membrane Protein (GLMP) | WB; IHC; ICC; IP. | |
| Assay Kits | SET758Mu | ELISA Kit for Glycosylated Lysosomal Membrane Protein (GLMP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Glycosylated Lysosomal Membrane Protein (GLMP) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Glycosylated Lysosomal Membrane Protein (GLMP) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Glycosylated Lysosomal Membrane Protein (GLMP) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Glycosylated Lysosomal Membrane Protein (GLMP) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Glycosylated Lysosomal Membrane Protein (GLMP) | ELISA Kit Customized Service Offer |
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
- "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator."BMC Mol. Biol. 8:106-106(2007) [PubMed] [Europe PMC] [Abstract]
- "Integral and associated lysosomal membrane proteins."Traffic 8:1676-1686(2007) [PubMed] [Europe PMC] [Abstract]
- "A gene network regulating lysosomal biogenesis and function."Science 325:473-477(2009) [PubMed] [Europe PMC] [Abstract]