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SH3 And Cysteine Rich Domain Protein 3 (STAC3)

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SH3 And Cysteine Rich Domain Protein 3 (STAC3)
CCC T736
HGNC 28423
MGI 3606571
PubMed 23736855
RGD 1308964
UniProt Q96MF2
The Src homology 3 (SH3) domain is a highly conserved 60 amino acid protein domain that is organized into a β-barrel fold consisting of five or six β strands arranged as two tightly packed anti-parallel β sheets.
STAC3 is a 364 amino acid protein containing one phorbol-ester/DAG-type zinc finger and two SH3 (Src homology 3) domains. Existing as two alternatively spliced isoforms, STAC3 maps to human chromosome 12q13.3. Human chromosome 12 encodes over 1,400 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SH3 And Cysteine Rich Domain Protein 3 (STAC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SH3 And Cysteine Rich Domain Protein 3 (STAC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SH3 And Cysteine Rich Domain Protein 3 (STAC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SH3 And Cysteine Rich Domain Protein 3 (STAC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for SH3 And Cysteine Rich Domain Protein 3 (STAC3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SH3 And Cysteine Rich Domain Protein 3 (STAC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SH3 And Cysteine Rich Domain Protein 3 (STAC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SH3 And Cysteine Rich Domain Protein 3 (STAC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SH3 And Cysteine Rich Domain Protein 3 (STAC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for SH3 And Cysteine Rich Domain Protein 3 (STAC3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SH3 And Cysteine Rich Domain Protein 3 (STAC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SH3 And Cysteine Rich Domain Protein 3 (STAC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SH3 And Cysteine Rich Domain Protein 3 (STAC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SH3 And Cysteine Rich Domain Protein 3 (STAC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for SH3 And Cysteine Rich Domain Protein 3 (STAC3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Stac3 is a component of the excitation-contraction coupling machinery and mutated in Native American myopathy."Nat. Commun. 4:1952-1952(2013) [PubMed] [Europe PMC] [Abstract]
  5. "Solution structure of RSGI RUH-051, a C1 domain of STAC3 from human cDNA."Submitted (JUN-2006) to the PDB data bank