Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1)

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Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1)
ASPHD1 belongs to the aspartyl/asparaginyl beta-hydroxylase family. This gene is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins. Enhanced AAH gene activity is a common feature of human HCC and growth factor signaling through IRS-1 regulates AAH expression and increases motility and invasion of HCC cells. Therefore, AAH may represent an important target for regulating tumor growth in vivo.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aspartate Beta Hydroxylase Domain Containing Protein 1 (ASPHD1) ELISA Kit Customized Service Offer
  1. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]