≡

Nucleolar Protein 11 (NOL11)

[Edit]

L14

Nucleolar Protein 11 (NOL11)
CCC T649
HGNC 24557
MGI 1916229
PubMed 22916032
RGD 1584081
UniProt Q9H8H0
NOL11 is a nucleolar protein. Belongs to the WD repeat family.Three isoforms of the human protein are produced by alternative splicing, however, its function has not yet been determined.
A polyglutamine tract or polyQ tract is a portion of a protein consisting of a sequence of several glutamine units. A tract typically consists of about 10 to a few hundred such units.Several inheritable neurodegenerative disorders, the polyglutamine diseases, occur if a mutation causes a polyglutamine tract in a specific gene to become too long. Important examples of polyglutamine diseases are spinocerebellar ataxia and Huntington's disease. It is believed that cells cannot properly dispose of proteins with overly long polyglutamine tracts, which over time leads to damage in nerve cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleolar Protein 11 (NOL11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleolar Protein 11 (NOL11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleolar Protein 11 (NOL11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleolar Protein 11 (NOL11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleolar Protein 11 (NOL11) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleolar Protein 11 (NOL11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleolar Protein 11 (NOL11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleolar Protein 11 (NOL11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleolar Protein 11 (NOL11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleolar Protein 11 (NOL11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleolar Protein 11 (NOL11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleolar Protein 11 (NOL11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleolar Protein 11 (NOL11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleolar Protein 11 (NOL11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleolar Protein 11 (NOL11) ELISA Kit Customized Service Offer
  1. "Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer."Oncogene 23:7734-7745(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Functional proteomic analysis of human nucleolus."Mol. Biol. Cell 13:4100-4109(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing."PLoS Genet. 8:E1002892-E1002892(2012) [PubMed] [Europe PMC] [Abstract]