Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A)

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PPAPDC1; DPPL2; Phosphatidate phosphatase PPAPDC1A

Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A)
PPAPDC1A belongs to the PA-phosphatase related phosphoesterase family. Expressed mainly to the brain, kidney and testis, and to a lesser extent the bone marrow, thymus, prostate, liver and uterus. Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol.
The polyisoprenoid diphosphates farnesyl diphosphate (FPP) and geranylgeranyl diphosphate (GGPP) are intermediates in the synthesis of cholesterol and related sterols by the mevalonate pathway and precursors for the addition of isoprenyl anchors to many membrane proteins. In vitro, recombinant PDP1/PPAPDC2 preferentially hydrolyzed polyisoprenoid diphosphates, including FPP and GGPP over a variety of glycerol- and sphingo-phospholipid substrates.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidic Acid Phosphatase Type 2 Domain Containing Protein 1A (PPAPDC1A) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of DPPL1 and DPPL2, representatives of a novel type of mammalian phosphatidate phosphatase."Gene 399:174-180(2007) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]