Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1)

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Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1)
PHYHD1 belongs to the PhyH family. Probably acts as alpha-ketoglutatare-dependent dioxygenase. Phytanoyl-CoA hydroxylase, a peroxisomal protein that catalyzes the first step in the alpha-oxidation of phytanic acid, a branched-chain fatty acid. Because beta-oxidation is blocked by the methyl group at C-3, phytanic acid must first undergo decarboxylation via an alpha-oxidation mechanism catalyzed by PHYH.Both groups made use of expressed sequence tag (EST) database searching for identification of the full-length human cDNA sequence. The open reading frame encodes a 41.2-kD protein of 338 amino acids, which contains a cleavable peroxisomal targeting signal type 2 (PTS2).The structure and subcellular localization of the phytanic acid alpha-oxidation pathway long remained enigmatic, although it was generally assumed to involve phytanic acid and not its CoA-ester.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phytanoyl Coenzyme A Dioxygenase Domain Containing Protein 1 (PHYHD1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  5. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  6. "Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase."Biochem. Biophys. Res. Commun. 408:553-558(2011) [PubMed] [Europe PMC] [Abstract]