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Transmembrane And Coiled Coil Domains Protein 3 (TMCO3)

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C13orf11; Putative LAG1-interacting protein

Transmembrane And Coiled Coil Domains Protein 3 (TMCO3)
CCC T543
HGNC 20329
MGI 2444946
PubMed 23849371
RGD 1306586
UniProt Q6UWJ1
TMCO3 is a 677 amino acid multi-pass membrane protein that probably functions as a Na+/H+ antiporter. TMCO3 belongs to the monovalent cation:protein antiporter 2 transporter family, a moderately large family of which members all share a very similar function under normal physiological conditions. The gene encoding TMCO3 maps to human chromosome 13, which comprises nearly 4% of human DNA and contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. There are three isoforms of TMCO3 that are produced as a result of alternative splicing events.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane And Coiled Coil Domains Protein 3 (TMCO3) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]