Casein Kinase 1 Alpha 1 Like Protein (CSNK1a1L)

[Edit]

CK1

Casein Kinase 1 Alpha 1 Like Protein (CSNK1a1L)
CSNK1A1L, Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. Contains 1 protein kinase domain. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins.
Casein kinase 1 alpha has been suggested to play a role in phosphorylation of Disheveled in the Wnt signaling pathway .Jia et al. (2004) showed that protein kinase A (PKA) and casein kinase I (CKI) regulate Smo cell surface accumulation and activity in response to hedgehog (Hh). Blocking PKA or CKI activity in the Drosophila wing disc prevented Hh-induced Smo accumulation and attenuated pathway activity, whereas increasing PKA activity promoted Smo accumulation and pathway activation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Casein Kinase 1 Alpha 1 Like Protein (CSNK1a1L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Casein Kinase 1 Alpha 1 Like Protein (CSNK1a1L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Casein Kinase 1 Alpha 1 Like Protein (CSNK1a1L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Casein Kinase 1 Alpha 1 Like Protein (CSNK1a1L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Casein Kinase 1 Alpha 1 Like Protein (CSNK1a1L) ELISA Kit Customized Service Offer
  1. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
  4. "Patterns of somatic mutation in human cancer genomes." Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]