![Hedgehog Interacting Protein Like Protein 1 (HHIPL1)](/upload/item/img/Hedgehog-Interacting-Protein-Like-Protein-1-(HHIPL1)-87517.jpg)
L, Belongs to the HHIP family. Contains 1 SRCR domain. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic development, including anteroposterior patterns of limbs and regulation of left-right asymmetry.Hip cDNA encodes a type I transmembrane glycoprotein, which is expressed in all hedgehog target tissues and binds all 3 mammalian hedgehog proteins with an affinity similar to that of the Ptc protein. Hip expression is upregulated in response to Hh signaling.
Ectopic expression of Hip in transgenic mice results in severe skeletal defects similar to those observed in Indian hedgehog (IHH) mutants, demonstrating that Hip is involved in the attenuation of hedgehog signaling.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Hedgehog Interacting Protein Like Protein 1 (HHIPL1) | ELISA Kit Customized Service Offer |
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 8:85-95(2001) [PubMed] [Europe PMC] [Abstract]
- "Comparative genomics on HHIP family orthologs."Int. J. Mol. Med. 17:391-395(2006) [PubMed] [Europe PMC] [Abstract]