Tandem C2 Domains Nuclear Protein (TC2N)

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C14orf47; MTAC2D1; Tac2-N; C2CD1; Tandem C2 protein in nucleus; Membrane Targeting (Tandem) C2 Domain Containing 1; C2 Calcium-Dependent Domain Containing 1

Tandem C2 Domains Nuclear Protein (TC2N)
, an atypical C-type tandem C2 protein localized in the nucleus. Syts are membrane proteins that possess tandem C2 domains (C2AB) implicated in calciumdependent phospholipid binding.Sequence analysis indicates three different C2AB classes, the members of which share a high degree of sequence similarity. All the other C2ABs are highly divergent in sequence. Nearly half of the Syt family does not exhibit calcium/phospholipid binding in comparison to Syt I, the major brain isoform.Structurally, a C2 domain consists of eight beta-strands arranged in a barrel-like structure with a total amino acid length of about 125-130. C2 domains were initially identified in the protein kinase C (PKC) family and are found in more than one hundred intracellular proteins including membrane trafficking proteins.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tandem C2 Domains Nuclear Protein (TC2N) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tandem C2 Domains Nuclear Protein (TC2N) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tandem C2 Domains Nuclear Protein (TC2N) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tandem C2 Domains Nuclear Protein (TC2N) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tandem C2 Domains Nuclear Protein (TC2N) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tandem C2 Domains Nuclear Protein (TC2N) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tandem C2 Domains Nuclear Protein (TC2N) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tandem C2 Domains Nuclear Protein (TC2N) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tandem C2 Domains Nuclear Protein (TC2N) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tandem C2 Domains Nuclear Protein (TC2N) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tandem C2 Domains Nuclear Protein (TC2N) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tandem C2 Domains Nuclear Protein (TC2N) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tandem C2 Domains Nuclear Protein (TC2N) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tandem C2 Domains Nuclear Protein (TC2N) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tandem C2 Domains Nuclear Protein (TC2N) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]