Tubulin Tyrosine Ligase Like Protein 11 (TTLL11)

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C9orf20; Tubulin polyglutamylase TTLL11

Tubulin Tyrosine Ligase Like Protein 11 (TTLL11)
TTLL11, Belongs to the tubulin--tyrosine ligase family. Contains 1 TTL domain. Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction. Certain proteins can undergo polyglycylation and polyglutamylation. Polyglutamylases (glutamate ligases) have recently been identified in a family of tubulin tyrosine ligase-like (TTLL) proteins. However, no polyglycylase (glycine ligase) has yet been reported.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulin Tyrosine Ligase Like Protein 11 (TTLL11) ELISA Kit Customized Service Offer
  1. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  2. "CSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish development."Mol. Biol. Cell 23:2122-2130(2012) [PubMed] [Europe PMC] [Abstract]