Tripartite Motif Containing Protein 69 (TRIM69)
[Edit]RNF36; Trif; HSD34; TRIMLESS; Ring Finger Protein 36; RFP-like domain-containing protein trimless; E3 ubiquitin-protein ligase TRIM69
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TRIM69encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. TRIM69 is a 500 amino acid protein that belongs to the TRIM family and contains one RINGtype zinc finger and one B30.2/SPRY domain. Localizing to nuclear speckles, TRIM69 interacts with PML (promyelocytic leukemia) and is thought to play a role in spermatogenesis and, when overexpressed, may be involved in apoptosis. TRIM69 is subject to posttranslational phosphorylation, an event which is necessary for TRIM69 nuclear localization. Multiple isoforms of TRIM69 exist due to alternative splicing events.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Tripartite Motif Containing Protein 69 (TRIM69) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Tripartite Motif Containing Protein 69 (TRIM69) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Tripartite Motif Containing Protein 69 (TRIM69) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Tripartite Motif Containing Protein 69 (TRIM69) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Tripartite Motif Containing Protein 69 (TRIM69) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Tripartite Motif Containing Protein 69 (TRIM69) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Tripartite Motif Containing Protein 69 (TRIM69) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Tripartite Motif Containing Protein 69 (TRIM69) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Tripartite Motif Containing Protein 69 (TRIM69) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Tripartite Motif Containing Protein 69 (TRIM69) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Tripartite Motif Containing Protein 69 (TRIM69) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Tripartite Motif Containing Protein 69 (TRIM69) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Tripartite Motif Containing Protein 69 (TRIM69) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Tripartite Motif Containing Protein 69 (TRIM69) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Tripartite Motif Containing Protein 69 (TRIM69) | ELISA Kit Customized Service Offer |
- "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Characterisation of human RING finger protein TRIM69, a novel testis E3 ubiquitin ligase and its subcellular localisation."Biochem. Biophys. Res. Commun. 429:6-11(2012) [PubMed] [Europe PMC] [Abstract]