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Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10)

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C22orf16; N27C7-4

Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10)
CCC T343
HGNC 15559
PubMed 20888800
RGD 1359417
UniProt Q8WYQ3
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Transloacations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The gene product has been provisionally designated CHCHD10 pending further characterization.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Coiled Coil Helix Coiled Coil Helix Domain Containing Protein 10 (CHCHD10) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement." Brain 137:2329-2345(2014) [PubMed] [Europe PMC] [Abstract]
  4. "Late onset spinal motor neuronopathy is caused by mutation in CHCHD10."Ann. Neurol. 77:163-172(2015) [PubMed] [Europe PMC] [Abstract]
  5. "Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy."Neurogenetics 16:1-9(2015) [PubMed] [Europe PMC] [Abstract]
  6. "Screening of CHCHD10 in a French cohort confirms the involvement of this gene in frontotemporal dementia with amyotrophic lateral sclerosis patients."Neurobiol. Aging 0:0-0(2014) [PubMed] [Europe PMC] [Abstract]