≡

PR Domain Containing Protein 15 (PRDM15)

[Edit]

ZNF298; C21orf83; PFM15

PR Domain Containing Protein 15 (PRDM15)
CCC T093
HGNC 13999
MGI 1930121
PubMed 23616578
RGD 1310055
UniProt P57071
The PR-domain containing proteins (PRDMs) have a common involvement in the modulation of gene activities. A PR-domain family member usually produces two products, called PR-plus and PR-minus, which differ by the presence or absence of the PR domain, respectively. The PR-plus product is underexpressed or disrupted in cancer cells, whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, which is a result of either genetic or epigenetic events, appears to be a determining factor of malignancy. is a 1507 amino acid protein belonging to the PRDM family. Localizing to the nucleus, PRDM15 contains 16 C2H2-type zinc fingers and one SET domain. It is believed to participate in transcriptional regulation and may be involved in cell differentiation and tumorigenesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PR Domain Containing Protein 15 (PRDM15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PR Domain Containing Protein 15 (PRDM15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PR Domain Containing Protein 15 (PRDM15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PR Domain Containing Protein 15 (PRDM15) CLIA Kit Customized Service Offer
n/a ELISA Kit for PR Domain Containing Protein 15 (PRDM15) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PR Domain Containing Protein 15 (PRDM15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PR Domain Containing Protein 15 (PRDM15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PR Domain Containing Protein 15 (PRDM15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PR Domain Containing Protein 15 (PRDM15) CLIA Kit Customized Service Offer
n/a ELISA Kit for PR Domain Containing Protein 15 (PRDM15) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PR Domain Containing Protein 15 (PRDM15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PR Domain Containing Protein 15 (PRDM15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PR Domain Containing Protein 15 (PRDM15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PR Domain Containing Protein 15 (PRDM15) CLIA Kit Customized Service Offer
n/a ELISA Kit for PR Domain Containing Protein 15 (PRDM15) ELISA Kit Customized Service Offer
  1. "Annotation of human chromosome 21 for relevance to Down syndrome: gene structure and expression analysis."Genomics 79:833-843(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Identification of a novel zinc finger protein gene (ZNF298) in the GAP2 of human chromosome 21q."Biochem. Biophys. Res. Commun. 332:557-568(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of human chromosome 21." Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Nineteen additional unpredicted transcripts from human chromosome 21."Genomics 79:824-832(2002) [PubMed] [Europe PMC] [Abstract]